Amoxicillin vs Co-trimoxazole(Trimethoprim/sulfamethoxazole)

National NHS prescribing compared (Prescription Cost Analysis)

Data updated March 2026

Amoxicillin was dispensed 26.8× as often as Co-trimoxazole(Trimethoprim/sulfamethoxazole) in March 2026 — 752,911 items versus 28,105 in England.

752,911items

Amoxicillin · March 2026

NHSBSA Prescription Cost Analysis

28,105items

Co-trimoxazole(Trimethoprim/sulfamethoxazole) · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Amoxicillin versus Co-trimoxazole(Trimethoprim/sulfamethoxazole): national items dispensed by month

▬ Amoxicillin · ╌ Co-trimoxazole(Trimethoprim/sulfamethoxazole)

Source: NHSBSA Prescription Cost Analysis, to March 2026

Amoxicillin versus Co-trimoxazole(Trimethoprim/sulfamethoxazole), March 2026
Measure	Amoxicillin	Co-trimoxazole(Trimethoprim/sulfamethoxazole)
Items, March 2026	752,911	28,105
Items, last 12 months	8,312,633	312,035
Net ingredient cost, March 2026	£914,328	£87,786