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Hospital medicines spending

Secondary Care Medicines Data (SCMD) · indicative cost · June 2025 – May 2026
Data updated May 2026

What NHS hospitals in England actually use, by indicative cost. Over the 12 months to May 2026, the highest was Adalimumab 40mg/0.4ml solution for injection pre-filled disposable devices (£740,900,919). This is a different dataset from hospital prescribing dispensed in the community: it covers medicines issued within secondary care.

Cost is indicative — actual hospital medicine prices are commercially confidential, so these figures are estimated from list prices and understate true spend on some drugs. See methodology.

Figure 1. National hospital medicines indicative cost by month

£0 £1,212.7m £2,425.3m Apr 2021 Jan 2022 Nov 2022 Aug 2023 May 2024 Feb 2025 Jul 2026 £2,425,349,659.2 Apr 2021: £2,138.9m May 2021: £1,544m Jun 2021: £2,114.3m Jul 2021: £1,781.6m Aug 2021: £1,493.9m Sep 2021: £1,465.4m Oct 2021: £1,358.8m Nov 2021: £1,500.9m Dec 2021: £1,441.1m Jan 2022: £1,403.8m Feb 2022: £1,490m Mar 2022: £1,567.1m Apr 2022: £1,351.7m Jun 2022: £1,410.8m Jul 2022: £1,459.3m Aug 2022: £1,537.8m Sep 2022: £1,493.3m Oct 2022: £1,467.3m Nov 2022: £1,565.9m Dec 2022: £1,433.9m Jan 2023: £1,583.3m Feb 2023: £1,421.7m Mar 2023: £1,693m Apr 2023: £1,501.6m May 2023: £1,665.1m Jun 2023: £1,660.4m Jul 2023: £1,630.3m Aug 2023: £1,697.1m Sep 2023: £1,612.4m Oct 2023: £1,646.9m Nov 2023: £1,706.1m Dec 2023: £1,504.2m Jan 2024: £1,746.3m Feb 2024: £1,715.9m Mar 2024: £1,673.7m Apr 2024: £1,746.6m May 2024: £1,602.2m Jun 2024: £1,636.5m Jul 2024: £1,876.8m Aug 2024: £1,825.1m Sep 2024: £1,853.4m Oct 2024: £2,009.9m Nov 2024: £1,845.9m Dec 2024: £1,924.5m Jan 2025: £2,118.9m Feb 2025: £1,861.5m Mar 2025: £1,997.7m Apr 2025: £1,951.5m May 2025: £1,952.1m Jun 2025: £2,055.6m Jul 2025: £2,144.1m Aug 2025: £2,052.3m Sep 2025: £2,112.1m Oct 2025: £2,297.2m Nov 2025: £1,965.6m Dec 2025: £2,154m Jan 2026: £2,193.8m Feb 2026: £2,007.9m Mar 2026: £2,312.3m Apr 2026: £2,159.1m May 2026: £2,040.9m Jun 2026: £2,286.2m Jul 2026: £2,425.3m

Source: NHSBSA Secondary Care Medicines Data, to May 2026

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Download the monthly series and the biggest cost movers as CSV from the hospital medicines dataset.

Highest indicative cost, June 2025 – May 2026

Download CSV
NHS hospital medicines by indicative cost, June 2025 – May 2026
# Medicine Indicative cost (12 months)
1 Adalimumab 40mg/0.4ml solution for injection pre-filled disposable devices £740,900,919
2 Pembrolizumab 100mg/4ml solution for infusion vials £547,671,239
3 Daratumumab 1.8g/15ml solution for injection vials £518,064,912
4 Generic Kaftrio 75mg/50mg/100mg tablets £492,854,082
5 Ivacaftor 150mg tablets £425,532,250
6 Enzalutamide 40mg tablets £391,191,195
7 Infliximab 100mg powder for solution for infusion vials £379,471,202
8 Faricimab 21mg/0.175ml solution for injection pre-filled syringes £354,130,375
9 Adalimumab 40mg/0.8ml solution for injection pre-filled disposable devices £324,940,944
10 Aflibercept 3.6mg/90microlitres solution for injection pre-filled syringes £298,283,978
11 Pertuzumab 600mg/10ml / Trastuzumab 600mg/10ml solution for injection vials £253,802,720
12 Tafamidis 61mg capsules £248,451,894
13 Ustekinumab 90mg/1ml solution for injection pre-filled syringes £241,468,796
14 Emtricitabine 200mg / Tenofovir disoproxil 245mg tablets £240,717,708
15 Lenalidomide 10mg capsules £229,202,325
16 Tebentafusp 100micrograms/0.5ml solution for infusion vials £219,945,112
17 Darolutamide 300mg tablets £207,776,259
18 Bictegravir 50mg / Emtricitabine 200mg / Tenofovir alafenamide 25mg tablets £206,906,487
19 Etanercept 50mg/1ml solution for injection pre-filled disposable devices £199,538,063
20 Acalabrutinib 100mg tablets £198,591,449
21 Ofatumumab 20mg/0.4ml solution for injection pre-filled disposable devices £191,936,993
22 Dupilumab 300mg/2ml solution for injection pre-filled disposable devices £183,901,409
23 Dolutegravir 50mg / Lamivudine 300mg tablets £176,478,667
24 Generic Alyftrek 125mg/50mg/10mg tablets £172,045,307
25 Ocrelizumab 300mg/10ml solution for infusion vials £171,084,430
26 Nivolumab 240mg/24ml solution for infusion vials £158,200,529
27 Vedolizumab 300mg powder for solution for infusion vials £151,519,231
28 Zanubrutinib 80mg capsules £138,679,542
29 Emicizumab 150mg/1ml solution for injection vials £138,601,991
30 Emicizumab 60mg/0.4ml solution for injection vials £137,667,269
31 Sofosbuvir 400mg / Velpatasvir 100mg tablets £131,251,561
32 Osimertinib 80mg tablets £131,094,463
33 Emicizumab 105mg/0.7ml solution for injection vials £128,239,146
34 Nintedanib 150mg capsules £128,115,251
35 Abiraterone 500mg tablets £126,910,815
36 Durvalumab 500mg/10ml solution for infusion vials £125,093,768
37 Secukinumab 300mg/2ml solution for injection pre-filled disposable devices £122,823,773
38 Rituximab 500mg/50ml solution for infusion vials £119,460,353
39 Normal immunoglobulin human 20g/200ml solution for infusion bottles £119,146,302
40 Ribociclib 200mg tablets £118,812,608
41 Risdiplam 750micrograms/ml oral solution sugar free £118,483,311
42 Polatuzumab vedotin 140mg powder for solution for infusion vials £114,754,468
43 Apalutamide 60mg tablets £114,273,729
44 Infliximab 120mg/1ml solution for injection pre-filled disposable devices £112,365,935
45 Lenalidomide 5mg capsules £109,332,131
46 Vedolizumab 108mg/0.68ml solution for injection pre-filled disposable devices £109,010,288
47 Etranacogene dezaparvovec 100 tera genome copies/10ml solution for infusion vials £106,600,000
48 Benralizumab 30mg/1ml solution for injection pre-filled disposable devices £106,367,640
49 Aflibercept 6.6mg/165microlitres solution for injection pre-filled syringes £105,647,112
50 Chorionic gonadotrophin 5,000unit powder and solvent for solution for injection pre-filled syringes £105,109,605
51 Upadacitinib 30mg modified-release tablets £104,104,951
52 Piperacillin 4g / Tazobactam 500mg powder for solution for infusion vials £102,931,612
53 Ravulizumab 1.1g/11ml solution for infusion vials £102,267,502
54 Risankizumab 360mg/2.4ml solution for injection cartridges £101,217,076
55 Abemaciclib 100mg tablets £99,243,321
56 Dimethyl fumarate 240mg gastro-resistant capsules £97,856,076
57 Tezepelumab 210mg/1.91ml solution for injection pre-filled disposable devices £97,298,780
58 Evolocumab 140mg/1ml solution for injection pre-filled disposable devices £91,949,086
59 Atezolizumab 1.875g/15ml solution for injection vials £89,611,304
60 Nintedanib 100mg capsules £84,445,381
61 Vutrisiran 25mg/0.5ml solution for injection pre-filled syringes £81,770,593
62 Nivolumab 600mg/5ml solution for injection vials £81,714,802
63 Aflibercept 21mg/184microlitres solution for injection pre-filled syringes £80,799,832
64 Apalutamide 240mg tablets £79,437,391
65 Normal immunoglobulin human 20g/200ml solution for infusion vials £78,901,182
66 Isatuximab 500mg/25ml solution for infusion vials £77,408,254
67 Imatinib 400mg tablets £76,318,839
68 Dostarlimab 500mg/10ml solution for infusion vials £75,293,063
69 Dolutegravir 50mg tablets £75,246,223
70 Risankizumab 150mg/1ml solution for injection pre-filled disposable devices £75,219,525
71 Upadacitinib 15mg modified-release tablets £74,811,844
72 Abemaciclib 150mg tablets £73,726,137
73 Venetoclax 100mg tablets £72,511,732
74 Ocrelizumab 920mg/23ml solution for injection vials £69,991,480
75 Olaparib 150mg tablets £66,773,367
76 Burosumab 30mg/1ml solution for injection vials £66,287,760
77 Avacopan 10mg capsules £65,603,511
78 Axicabtagene ciloleucel 40million-200million cells/68ml dispersion for infusion bags £64,503,730
79 Bevacizumab 400mg/16ml solution for infusion vials £63,931,335
80 Ustekinumab 130mg/26ml solution for infusion vials £63,677,047
81 Posaconazole 100mg gastro-resistant tablets £63,593,152
82 Trastuzumab deruxtecan 100mg powder for solution for infusion vials £63,393,623
83 Abemaciclib 50mg tablets £62,930,612
84 Trastuzumab 600mg/5ml solution for injection vials £62,639,728
85 Ibrutinib 420mg tablets £62,466,839
86 Avelumab 200mg/10ml solution for infusion vials £62,381,184
87 Tocilizumab 162mg/0.9ml solution for injection pre-filled disposable devices £61,986,010
88 Iohexol 755mg/ml (Iodine 350mg/ml) solution for injection 500ml plastic bottles £61,514,965
89 Dupilumab 300mg/2ml solution for injection pre-filled syringes £60,532,576
90 Filgrastim 30million units/0.5ml solution for injection pre-filled syringes £60,530,529
91 Elbasvir 50mg / Grazoprevir 100mg tablets £59,752,149
92 Guselkumab 100mg/1ml solution for injection pre-filled disposable devices £59,672,250
93 Lenalidomide 15mg capsules £58,311,210
94 Ipilimumab 50mg/10ml solution for infusion vials £58,086,225
95 Ipilimumab 200mg/40ml solution for infusion vials £58,039,875
96 Entecavir 500microgram tablets £57,731,721
97 Lanreotide 120mg/0.5ml solution for injection pre-filled syringes £57,651,736
98 Meropenem 1g powder for solution for injection vials £57,546,704
99 Nivolumab 240mg/20ml / Relatlimab 80mg/20ml solution for infusion vials £57,498,558
100 Secukinumab 150mg/1ml solution for injection pre-filled disposable devices £56,971,871