Sofosbuvir 400mg / Velpatasvir 100mg tablets
NHS hospitals in England used £130,676,149 of indicative cost of Sofosbuvir 400mg / Velpatasvir 100mg tablets in the 12 months to July 2026, about 0.5% of all hospital medicines spend. That is up 0.3% on the previous 12 months.
Indicative cost · 12 months
Quantity (VMP units) · 12 months
Share of hospital medicines spend
Figure 1. Sofosbuvir 400mg / Velpatasvir 100mg tablets: NHS hospital indicative cost by month (£ millions)
Source: NHSBSA Secondary Care Medicines Data, to July 2026
Cost is indicative — actual hospital medicine prices are commercially confidential, so these figures are estimated from list prices. See methodology.
NHS trusts using Sofosbuvir 400mg / Velpatasvir 100mg tablets most
By indicative cost over the 12 months to July 2026.
| NHS trust | Indicative cost (12 months) |
|---|---|
| Manchester University Nhs Ft | £7,956,089 |
| The Newcastle Upon Tyne Hpl Nhs Found Tr | £7,406,193 |
| Univ Hpl B/Ham Nhs Foundation Trust | £7,380,206 |
| Aintree University Hospital Nhs Ft | £4,651,609 |
| South Tees Hosp Nhs Foundation Trust | £4,547,662 |
| Nottingham University Hospitals Trust | £4,053,916 |
| Univ Hpls Bristol Nhs Foundation Trust | £3,391,257 |
| Leeds Teaching Hpls Nhs Trust | £3,209,350 |
| King's College Hpl Nhs Foundation Trust | £3,144,384 |
| Royal Surrey County Hosp Nhs Found Trust | £2,936,491 |
The primary-care picture
Sofosbuvir is also dispensed in the community. See the national primary-care prescribing volume, cost and trend on the Sofosbuvir medicine page.