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Independent analysis of NHS open data
PharmaInsight

Dolutegravir 50mg / Lamivudine 300mg tablets

Secondary Care Medicines Data (SCMD) · indicative cost
Data updated April 2026

NHS hospitals in England used £173,732,663 of indicative cost of Dolutegravir 50mg / Lamivudine 300mg tablets in the 12 months to April 2026, about 0.7% of all hospital medicines spend. That is up 31.8% on the previous 12 months.

£173,732,663 +31.8%

Indicative cost · 12 months

7,941,945units

Quantity (VMP units) · 12 months

0.7%

Share of hospital medicines spend

Figure 1. Dolutegravir 50mg / Lamivudine 300mg tablets: NHS hospital indicative cost by month (£ millions)

£0m £8.4m £16.8m Apr 2021 Jan 2022 Oct 2022 Jul 2023 Apr 2024 Jan 2025 Apr 2026 £16.2m Apr 2021: £1.8m May 2021: £2.5m Jun 2021: £2.8m Jul 2021: £2.6m Aug 2021: £2.5m Sep 2021: £2.9m Oct 2021: £3.3m Nov 2021: £3.2m Dec 2021: £3.0m Jan 2022: £3.4m Feb 2022: £3.4m Mar 2022: £4.5m Apr 2022: £3.9m May 2022: £4.9m Jun 2022: £4.6m Jul 2022: £4.9m Aug 2022: £5.2m Sep 2022: £5.2m Oct 2022: £5.7m Nov 2022: £6.0m Dec 2022: £5.3m Jan 2023: £6.3m Feb 2023: £5.8m Mar 2023: £7.2m Apr 2023: £6.3m May 2023: £7.1m Jun 2023: £7.3m Jul 2023: £7.5m Aug 2023: £7.8m Sep 2023: £7.0m Oct 2023: £7.9m Nov 2023: £8.2m Dec 2023: £7.1m Jan 2024: £8.8m Feb 2024: £8.2m Mar 2024: £8.7m Apr 2024: £9.2m May 2024: £9.2m Jun 2024: £8.9m Jul 2024: £10.5m Aug 2024: £9.8m Sep 2024: £10.3m Oct 2024: £12.0m Nov 2024: £11.3m Dec 2024: £10.9m Jan 2025: £11.6m Feb 2025: £11.5m Mar 2025: £12.2m Apr 2025: £13.7m May 2025: £12.9m Jun 2025: £12.6m Jul 2025: £14.7m Aug 2025: £13.3m Sep 2025: £13.9m Oct 2025: £14.7m Nov 2025: £14.8m Dec 2025: £14.1m Jan 2026: £15.4m Feb 2026: £14.4m Mar 2026: £16.8m Apr 2026: £16.2m

Source: NHSBSA Secondary Care Medicines Data, to April 2026

Cost is indicative — actual hospital medicine prices are commercially confidential, so these figures are estimated from list prices. See methodology.

NHS trusts using Dolutegravir 50mg / Lamivudine 300mg tablets most

By indicative cost over the 12 months to April 2026.

NHS trusts using Dolutegravir 50mg / Lamivudine 300mg tablets most, by indicative cost
NHS trustIndicative cost (12 months)
Chelsea & Westminster Hospital Nhs Ft £21,535,584
Royal Free London Nhs Foundation Trust £11,759,172
Manchester University Nhs Ft £7,742,838
University College London Foundation Tr £7,250,184
Ctrl & N W London Nhs Foundation Trust £5,636,355
University Hpls Of Leicester Nhs Trust £5,459,010
Aintree University Hospital Nhs Ft £5,408,280
North Bristol Nhs Trust £5,333,118
Univ Hpl B/Ham Nhs Foundation Trust £5,170,563
Barts Health Nhs Trust £4,883,230

The primary-care picture

Dolutegravir is also dispensed in the community. See the national primary-care prescribing volume, cost and trend on the Dolutegravir medicine page.