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Independent analysis of NHS open data
PharmaInsight

Upadacitinib 15mg modified-release tablets

Secondary Care Medicines Data (SCMD) · indicative cost
Data updated April 2026

NHS hospitals in England used £73,859,614 of indicative cost of Upadacitinib 15mg modified-release tablets in the 12 months to April 2026, about 0.3% of all hospital medicines spend. That is up 29.6% on the previous 12 months.

£73,859,614 +29.6%

Indicative cost · 12 months

2,567,244units

Quantity (VMP units) · 12 months

0.3%

Share of hospital medicines spend

Figure 1. Upadacitinib 15mg modified-release tablets: NHS hospital indicative cost by month (£ millions)

£0m £3.6m £7.3m Apr 2021 Jan 2022 Oct 2022 Jul 2023 Apr 2024 Jan 2025 Apr 2026 £6.8m Apr 2021: £0.2m May 2021: £0.4m Jun 2021: £0.5m Jul 2021: £0.4m Aug 2021: £0.5m Sep 2021: £0.5m Oct 2021: £0.6m Nov 2021: £0.9m Dec 2021: £0.7m Jan 2022: £0.7m Feb 2022: £0.8m Mar 2022: £1.1m Apr 2022: £0.9m May 2022: £1.1m Jun 2022: £1.1m Jul 2022: £1.1m Aug 2022: £1.6m Sep 2022: £1.9m Oct 2022: £1.8m Nov 2022: £1.9m Dec 2022: £1.5m Jan 2023: £2.1m Feb 2023: £2.3m Mar 2023: £2.8m Apr 2023: £2.4m May 2023: £2.6m Jun 2023: £2.5m Jul 2023: £3.3m Aug 2023: £2.7m Sep 2023: £3.1m Oct 2023: £2.8m Nov 2023: £3.4m Dec 2023: £2.7m Jan 2024: £3.5m Feb 2024: £3.4m Mar 2024: £3.4m Apr 2024: £3.8m May 2024: £3.9m Jun 2024: £3.8m Jul 2024: £4.2m Aug 2024: £4.4m Sep 2024: £4.5m Oct 2024: £5.3m Nov 2024: £4.8m Dec 2024: £5.3m Jan 2025: £5.5m Feb 2025: £4.6m Mar 2025: £5.5m Apr 2025: £5.2m May 2025: £5.3m Jun 2025: £5.6m Jul 2025: £5.8m Aug 2025: £5.6m Sep 2025: £5.9m Oct 2025: £6.3m Nov 2025: £6.2m Dec 2025: £6.2m Jan 2026: £6.9m Feb 2026: £6.0m Mar 2026: £7.3m Apr 2026: £6.8m

Source: NHSBSA Secondary Care Medicines Data, to April 2026

Cost is indicative — actual hospital medicine prices are commercially confidential, so these figures are estimated from list prices. See methodology.

NHS trusts using Upadacitinib 15mg modified-release tablets most

By indicative cost over the 12 months to April 2026.

NHS trusts using Upadacitinib 15mg modified-release tablets most, by indicative cost
NHS trustIndicative cost (12 months)
Sussex Community Nhs Foundation Trust £2,661,570
Royal Devon & Exeter Nhs Foundation Trst £2,458,799
Cambridge Univ Hosp Nhs Foundation Trust £2,004,233
Northampton General Hosp Trust £1,758,537
Luton & Dunstable Hospital Trust £1,735,176
Derby Teaching Hospitals Nhs Found Trust £1,699,732
University Hpls Of Leicester Nhs Trust £1,546,790
Leeds Teaching Hpls Nhs Trust £1,479,641
Western Sussex Hospitals Nhs Found Trust £1,379,119
Manchester University Nhs Ft £1,367,812

The primary-care picture

Upadacitinib is also dispensed in the community. See the national primary-care prescribing volume, cost and trend on the Upadacitinib medicine page.