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PharmaInsight

Amoxicillin vs Doxycycline hyclate

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Amoxicillin was dispensed 2.1× as often as Doxycycline hyclate in March 2026 — 752,911 items versus 360,207 in England.

752,911items

Amoxicillin · March 2026

NHSBSA Prescription Cost Analysis

360,207items

Doxycycline hyclate · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Amoxicillin versus Doxycycline hyclate: national items dispensed by month

▬ Amoxicillin   ·   ╌ Doxycycline hyclate

Doxycycline hycl… 752,911

Source: NHSBSA Prescription Cost Analysis, to March 2026

Amoxicillin versus Doxycycline hyclate, March 2026
Measure Amoxicillin Doxycycline hyclate
Items, March 2026 752,911 360,207
Items, last 12 months 8,312,633 3,966,758
Net ingredient cost, March 2026 £914,328 £400,436

See the full profile for Amoxicillin or Doxycycline hyclate.