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Independent analysis of NHS open data
PharmaInsight

Cenobamate vs Lamotrigine

National NHS prescribing compared (Prescription Cost Analysis)
Data updated May 2026

Lamotrigine was dispensed 37.8× as often as Cenobamate in May 2026 — 376,214 items versus 9,960 in England.

9,960items

Cenobamate · May 2026

NHSBSA Prescription Cost Analysis

376,214items

Lamotrigine · May 2026

NHSBSA Prescription Cost Analysis

Figure 1. Cenobamate versus Lamotrigine: national items dispensed by month

▬ Cenobamate   ·   ╌ Lamotrigine

0 199k 397k Jan 2022 Sep 2022 May 2023 Jan 2024 Sep 2024 May 2025 May 2026 Lamotrigine 9,960 Jan 2022: 3 Feb 2022: 7 Mar 2022: 26 Apr 2022: 30 May 2022: 83 Jun 2022: 111 Jul 2022: 169 Aug 2022: 213 Sep 2022: 277 Oct 2022: 308 Nov 2022: 479 Dec 2022: 559 Jan 2023: 708 Feb 2023: 818 Mar 2023: 1k Apr 2023: 999 May 2023: 1k Jun 2023: 2k Jul 2023: 2k Aug 2023: 2k Sep 2023: 2k Oct 2023: 2k Nov 2023: 2k Dec 2023: 3k Jan 2024: 3k Feb 2024: 3k Mar 2024: 3k Apr 2024: 4k May 2024: 4k Jun 2024: 4k Jul 2024: 5k Aug 2024: 5k Sep 2024: 5k Oct 2024: 5k Nov 2024: 5k Dec 2024: 6k Jan 2025: 6k Feb 2025: 6k Mar 2025: 6k Apr 2025: 7k May 2025: 7k Jun 2025: 7k Jul 2025: 8k Aug 2025: 7k Sep 2025: 8k Oct 2025: 9k Nov 2025: 8k Dec 2025: 9k Jan 2026: 9k Feb 2026: 9k Mar 2026: 10k Apr 2026: 10k May 2026: 10k

Source: NHSBSA Prescription Cost Analysis, to May 2026

Cenobamate versus Lamotrigine, May 2026
Measure Cenobamate Lamotrigine
Items, May 2026 9,960 376,214
Items, last 12 months 104,635 4,485,415
Net ingredient cost, May 2026 £1,668,920 £3,066,751

See the full profile for Cenobamate or Lamotrigine.