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PharmaInsight

Chlortalidone vs Eplerenone

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Eplerenone was dispensed 137.4× as often as Chlortalidone in March 2026 — 183,985 items versus 1,339 in England.

1,339items

Chlortalidone · March 2026

NHSBSA Prescription Cost Analysis

183,985items

Eplerenone · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Chlortalidone versus Eplerenone: national items dispensed by month

▬ Chlortalidone   ·   ╌ Eplerenone

Eplerenone 1,339

Source: NHSBSA Prescription Cost Analysis, to March 2026

Chlortalidone versus Eplerenone, March 2026
Measure Chlortalidone Eplerenone
Items, March 2026 1,339 183,985
Items, last 12 months 15,516 2,047,274
Net ingredient cost, March 2026 £41,695 £396,187

See the full profile for Chlortalidone or Eplerenone.