Co-amoxiclav (Amoxicillin/clavulanic acid) vs Doxycycline hyclate

National NHS prescribing compared (Prescription Cost Analysis)

Data updated March 2026

Doxycycline hyclate was dispensed 3.1× as often as Co-amoxiclav (Amoxicillin/clavulanic acid) in March 2026 — 360,207 items versus 115,278 in England.

115,278items

Co-amoxiclav (Amoxicillin/clavulanic acid) · March 2026

NHSBSA Prescription Cost Analysis

360,207items

Doxycycline hyclate · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Co-amoxiclav (Amoxicillin/clavulanic acid) versus Doxycycline hyclate: national items dispensed by month

▬ Co-amoxiclav (Amoxicillin/clavulanic acid) · ╌ Doxycycline hyclate

Source: NHSBSA Prescription Cost Analysis, to March 2026

Co-amoxiclav (Amoxicillin/clavulanic acid) versus Doxycycline hyclate, March 2026
Measure	Co-amoxiclav (Amoxicillin/clavulanic acid)	Doxycycline hyclate
Items, March 2026	115,278	360,207
Items, last 12 months	1,324,285	3,966,758
Net ingredient cost, March 2026	£270,288	£400,436

See the full profile for Co-amoxiclav (Amoxicillin/clavulanic acid) or Doxycycline hyclate.