Co-phenotrope (Diphenox hydrochloride/atropine sulfate) vs Loperamide hydrochloride

National NHS prescribing compared (Prescription Cost Analysis)

Data updated May 2026

Loperamide hydrochloride was dispensed 2,217.8× as often as Co-phenotrope (Diphenox hydrochloride/atropine sulfate) in May 2026 — 135,287 items versus 61 in England.

61items

Co-phenotrope (Diphenox hydrochloride/atropine sulfate) · May 2026

NHSBSA Prescription Cost Analysis

135,287items

Loperamide hydrochloride · May 2026

NHSBSA Prescription Cost Analysis

Figure 1. Co-phenotrope (Diphenox hydrochloride/atropine sulfate) versus Loperamide hydrochloride: national items dispensed by month

▬ Co-phenotrope (Diphenox hydrochloride/atropine sulfate) · ╌ Loperamide hydrochloride

Source: NHSBSA Prescription Cost Analysis, to May 2026

Co-phenotrope (Diphenox hydrochloride/atropine sulfate) versus Loperamide hydrochloride, May 2026
Measure	Co-phenotrope (Diphenox hydrochloride/atropine sulfate)	Loperamide hydrochloride
Items, May 2026	61	135,287
Items, last 12 months	1,067	1,686,844
Net ingredient cost, May 2026	£17,037	£765,129

See the full profile for Co-phenotrope (Diphenox hydrochloride/atropine sulfate) or Loperamide hydrochloride.