Co-phenotrope (Diphenox hydrochloride/atropine sulfate) vs Loperamide hydrochloride

National NHS prescribing compared (Prescription Cost Analysis)

Data updated March 2026

Loperamide hydrochloride was dispensed 1,439.5× as often as Co-phenotrope (Diphenox hydrochloride/atropine sulfate) in March 2026 — 141,068 items versus 98 in England.

98items

Co-phenotrope (Diphenox hydrochloride/atropine sulfate) · March 2026

NHSBSA Prescription Cost Analysis

141,068items

Loperamide hydrochloride · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Co-phenotrope (Diphenox hydrochloride/atropine sulfate) versus Loperamide hydrochloride: national items dispensed by month

▬ Co-phenotrope (Diphenox hydrochloride/atropine sulfate) · ╌ Loperamide hydrochloride

Source: NHSBSA Prescription Cost Analysis, to March 2026

Co-phenotrope (Diphenox hydrochloride/atropine sulfate) versus Loperamide hydrochloride, March 2026
Measure	Co-phenotrope (Diphenox hydrochloride/atropine sulfate)	Loperamide hydrochloride
Items, March 2026	98	141,068
Items, last 12 months	1,100	1,696,127
Net ingredient cost, March 2026	£17,194	£772,884

See the full profile for Co-phenotrope (Diphenox hydrochloride/atropine sulfate) or Loperamide hydrochloride.