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Co-phenotrope (Diphenox hydrochloride/atropine sulfate) vs Loperamide hydrochloride and simeticone

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Loperamide hydrochloride and simeticone was dispensed 1.8× as often as Co-phenotrope (Diphenox hydrochloride/atropine sulfate) in March 2026 — 178 items versus 98 in England.

98items

Co-phenotrope (Diphenox hydrochloride/atropine sulfate) · March 2026

NHSBSA Prescription Cost Analysis

178items

Loperamide hydrochloride and simeticone · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Co-phenotrope (Diphenox hydrochloride/atropine sulfate) versus Loperamide hydrochloride and simeticone: national items dispensed by month

▬ Co-phenotrope (Diphenox hydrochloride/atropine sulfate)   ·   ╌ Loperamide hydrochloride and simeticone

Loperamide hydro… 98

Source: NHSBSA Prescription Cost Analysis, to March 2026

Co-phenotrope (Diphenox hydrochloride/atropine sulfate) versus Loperamide hydrochloride and simeticone, March 2026
Measure Co-phenotrope (Diphenox hydrochloride/atropine sulfate) Loperamide hydrochloride and simeticone
Items, March 2026 98 178
Items, last 12 months 1,100 2,335
Net ingredient cost, March 2026 £17,194 £5,204

See the full profile for Co-phenotrope (Diphenox hydrochloride/atropine sulfate) or Loperamide hydrochloride and simeticone.