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Independent analysis of NHS open data
PharmaInsight

Cyproheptadine hydrochloride vs Promethazine hydrochloride

National NHS prescribing compared (Prescription Cost Analysis)
Data updated May 2026

Promethazine hydrochloride was dispensed 1,269.2× as often as Cyproheptadine hydrochloride in May 2026 — 234,806 items versus 185 in England.

185items

Cyproheptadine hydrochloride · May 2026

NHSBSA Prescription Cost Analysis

234,806items

Promethazine hydrochloride · May 2026

NHSBSA Prescription Cost Analysis

Figure 1. Cyproheptadine hydrochloride versus Promethazine hydrochloride: national items dispensed by month

▬ Cyproheptadine hydrochloride   ·   ╌ Promethazine hydrochloride

0 127k 255k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 May 2026 Promethazine hyd… 185 Jan 2021: 212 Feb 2021: 161 Mar 2021: 199 Apr 2021: 226 May 2021: 183 Jun 2021: 221 Jul 2021: 229 Aug 2021: 206 Sep 2021: 225 Oct 2021: 209 Nov 2021: 217 Dec 2021: 239 Jan 2022: 218 Feb 2022: 204 Mar 2022: 214 Apr 2022: 201 May 2022: 237 Jun 2022: 213 Jul 2022: 219 Aug 2022: 233 Sep 2022: 187 Oct 2022: 233 Nov 2022: 200 Dec 2022: 188 Jan 2023: 211 Feb 2023: 179 Mar 2023: 223 Apr 2023: 225 May 2023: 215 Jun 2023: 231 Jul 2023: 229 Aug 2023: 223 Sep 2023: 227 Oct 2023: 210 Nov 2023: 243 Dec 2023: 222 Jan 2024: 243 Feb 2024: 217 Mar 2024: 204 Apr 2024: 232 May 2024: 159 Jun 2024: 127 Jul 2024: 118 Aug 2024: 113 Sep 2024: 79 Oct 2024: 121 Nov 2024: 171 Dec 2024: 154 Jan 2025: 163 Feb 2025: 164 Mar 2025: 156 Apr 2025: 177 May 2025: 184 Jun 2025: 175 Jul 2025: 187 Aug 2025: 148 Sep 2025: 186 Oct 2025: 192 Nov 2025: 173 Dec 2025: 183 Jan 2026: 185 Feb 2026: 164 Mar 2026: 200 Apr 2026: 203 May 2026: 185

Source: NHSBSA Prescription Cost Analysis, to May 2026

Cyproheptadine hydrochloride versus Promethazine hydrochloride, May 2026
Measure Cyproheptadine hydrochloride Promethazine hydrochloride
Items, May 2026 185 234,806
Items, last 12 months 2,181 2,912,461
Net ingredient cost, May 2026 £4,786 £437,542

See the full profile for Cyproheptadine hydrochloride or Promethazine hydrochloride.