Diphenhydramine hydrochloride vs Guaifenesin
National NHS prescribing compared (Prescription Cost Analysis)
Guaifenesin was dispensed 49.5× as often as Diphenhydramine hydrochloride in May 2026 — 99 items versus 2 in England.
2items
Diphenhydramine hydrochloride · May 2026
NHSBSA Prescription Cost Analysis
99items
Guaifenesin · May 2026
NHSBSA Prescription Cost Analysis
Figure 1. Diphenhydramine hydrochloride versus Guaifenesin: national items dispensed by month
▬ Diphenhydramine hydrochloride · ╌ Guaifenesin
Source: NHSBSA Prescription Cost Analysis, to May 2026
| Measure | Diphenhydramine hydrochloride | Guaifenesin |
|---|---|---|
| Items, May 2026 | 2 | 99 |
| Items, last 12 months | 21 | 1,416 |
| Net ingredient cost, May 2026 | £7 | £535 |
See the full profile for Diphenhydramine hydrochloride or Guaifenesin.