Diphenhydramine hydrochloride vs Guaifenesin
National NHS prescribing compared (Prescription Cost Analysis)
Guaifenesin was dispensed 69.5× as often as Diphenhydramine hydrochloride in March 2026 — 139 items versus 2 in England.
2items
Diphenhydramine hydrochloride · March 2026
NHSBSA Prescription Cost Analysis
139items
Guaifenesin · March 2026
NHSBSA Prescription Cost Analysis
Figure 1. Diphenhydramine hydrochloride versus Guaifenesin: national items dispensed by month
▬ Diphenhydramine hydrochloride · ╌ Guaifenesin
Source: NHSBSA Prescription Cost Analysis, to March 2026
| Measure | Diphenhydramine hydrochloride | Guaifenesin |
|---|---|---|
| Items, March 2026 | 2 | 139 |
| Items, last 12 months | 24 | 1,402 |
| Net ingredient cost, March 2026 | £8 | £795 |
See the full profile for Diphenhydramine hydrochloride or Guaifenesin.