Donepezil hydrochloride vs Rivastigmine
National NHS prescribing compared (Prescription Cost Analysis)
Donepezil hydrochloride was dispensed 4.8× as often as Rivastigmine in March 2026 — 177,911 items versus 36,834 in England.
177,911items
Donepezil hydrochloride · March 2026
NHSBSA Prescription Cost Analysis
36,834items
Rivastigmine · March 2026
NHSBSA Prescription Cost Analysis
Figure 1. Donepezil hydrochloride versus Rivastigmine: national items dispensed by month
▬ Donepezil hydrochloride · ╌ Rivastigmine
Source: NHSBSA Prescription Cost Analysis, to March 2026
| Measure | Donepezil hydrochloride | Rivastigmine |
|---|---|---|
| Items, March 2026 | 177,911 | 36,834 |
| Items, last 12 months | 2,111,868 | 437,272 |
| Net ingredient cost, March 2026 | £481,987 | £1,405,181 |
See the full profile for Donepezil hydrochloride or Rivastigmine.