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Doxycycline hyclate vs Co-trimoxazole(Trimethoprim/sulfamethoxazole)

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Doxycycline hyclate was dispensed 12.8× as often as Co-trimoxazole(Trimethoprim/sulfamethoxazole) in March 2026 — 360,207 items versus 28,105 in England.

360,207items

Doxycycline hyclate · March 2026

NHSBSA Prescription Cost Analysis

28,105items

Co-trimoxazole(Trimethoprim/sulfamethoxazole) · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Doxycycline hyclate versus Co-trimoxazole(Trimethoprim/sulfamethoxazole): national items dispensed by month

▬ Doxycycline hyclate   ·   ╌ Co-trimoxazole(Trimethoprim/sulfamethoxazole)

Co-trimoxazole(T… 360,207

Source: NHSBSA Prescription Cost Analysis, to March 2026

Doxycycline hyclate versus Co-trimoxazole(Trimethoprim/sulfamethoxazole), March 2026
Measure Doxycycline hyclate Co-trimoxazole(Trimethoprim/sulfamethoxazole)
Items, March 2026 360,207 28,105
Items, last 12 months 3,966,758 312,035
Net ingredient cost, March 2026 £400,436 £87,786

See the full profile for Doxycycline hyclate or Co-trimoxazole(Trimethoprim/sulfamethoxazole).