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PharmaInsight

Doxycycline hyclate vs Doxycycline monohydrate

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Doxycycline hyclate was dispensed 58.9× as often as Doxycycline monohydrate in March 2026 — 360,207 items versus 6,114 in England.

360,207items

Doxycycline hyclate · March 2026

NHSBSA Prescription Cost Analysis

6,114items

Doxycycline monohydrate · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Doxycycline hyclate versus Doxycycline monohydrate: national items dispensed by month

▬ Doxycycline hyclate   ·   ╌ Doxycycline monohydrate

Doxycycline mono… 360,207

Source: NHSBSA Prescription Cost Analysis, to March 2026

Doxycycline hyclate versus Doxycycline monohydrate, March 2026
Measure Doxycycline hyclate Doxycycline monohydrate
Items, March 2026 360,207 6,114
Items, last 12 months 3,966,758 68,317
Net ingredient cost, March 2026 £400,436 £95,558

See the full profile for Doxycycline hyclate or Doxycycline monohydrate.