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Independent analysis of NHS open data
PharmaInsight

Drospirenone vs Medroxyprogesterone acetate

National NHS prescribing compared (Prescription Cost Analysis)
Data updated May 2026

Medroxyprogesterone acetate was dispensed 5.3× as often as Drospirenone in May 2026 — 55,709 items versus 10,477 in England.

10,477items

Drospirenone · May 2026

NHSBSA Prescription Cost Analysis

55,709items

Medroxyprogesterone acetate · May 2026

NHSBSA Prescription Cost Analysis

Figure 1. Drospirenone versus Medroxyprogesterone acetate: national items dispensed by month

▬ Drospirenone   ·   ╌ Medroxyprogesterone acetate

0 36k 73k Jan 2024 Jun 2024 Nov 2024 Apr 2025 Sep 2025 May 2026 Medroxyprogester… 10,477 Jan 2024: 3 Feb 2024: 170 Mar 2024: 290 Apr 2024: 411 May 2024: 548 Jun 2024: 727 Jul 2024: 879 Aug 2024: 908 Sep 2024: 1k Oct 2024: 1k Nov 2024: 1k Dec 2024: 2k Jan 2025: 2k Feb 2025: 2k Mar 2025: 3k Apr 2025: 3k May 2025: 3k Jun 2025: 4k Jul 2025: 4k Aug 2025: 4k Sep 2025: 5k Oct 2025: 6k Nov 2025: 6k Dec 2025: 7k Jan 2026: 7k Feb 2026: 8k Mar 2026: 9k Apr 2026: 10k May 2026: 10k

Source: NHSBSA Prescription Cost Analysis, to May 2026

Drospirenone versus Medroxyprogesterone acetate, May 2026
Measure Drospirenone Medroxyprogesterone acetate
Items, May 2026 10,477 55,709
Items, last 12 months 80,002 719,261
Net ingredient cost, May 2026 £181,378 £361,619

See the full profile for Drospirenone or Medroxyprogesterone acetate.