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Independent analysis of NHS open data
PharmaInsight

Eplerenone vs Spironolactone with thiazides

National NHS prescribing compared (Prescription Cost Analysis)
Data updated June 2026

Eplerenone was dispensed 191,307.0× as often as Spironolactone with thiazides in June 2026 — 191,307 items versus 1 in England.

191,307items

Eplerenone · June 2026

NHSBSA Prescription Cost Analysis

1items

Spironolactone with thiazides · June 2026

NHSBSA Prescription Cost Analysis

Figure 1. Eplerenone versus Spironolactone with thiazides: national items dispensed by month

▬ Eplerenone   ·   ╌ Spironolactone with thiazides

0 96k 191k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 Jun 2026 Spironolactone w… 191,307 Jan 2021: 78k Feb 2021: 74k Mar 2021: 83k Apr 2021: 82k May 2021: 81k Jun 2021: 85k Jul 2021: 86k Aug 2021: 83k Sep 2021: 88k Oct 2021: 85k Nov 2021: 90k Dec 2021: 95k Jan 2022: 90k Feb 2022: 86k Mar 2022: 97k Apr 2022: 94k May 2022: 98k Jun 2022: 97k Jul 2022: 98k Aug 2022: 103k Sep 2022: 103k Oct 2022: 103k Nov 2022: 106k Dec 2022: 109k Jan 2023: 109k Feb 2023: 102k Mar 2023: 117k Apr 2023: 107k May 2023: 116k Jun 2023: 119k Jul 2023: 117k Aug 2023: 122k Sep 2023: 123k Oct 2023: 125k Nov 2023: 126k Dec 2023: 129k Jan 2024: 133k Feb 2024: 127k Mar 2024: 130k Apr 2024: 136k May 2024: 141k Jun 2024: 134k Jul 2024: 147k Aug 2024: 144k Sep 2024: 142k Oct 2024: 152k Nov 2024: 147k Dec 2024: 154k Jan 2025: 157k Feb 2025: 143k Mar 2025: 153k Apr 2025: 157k May 2025: 164k Jun 2025: 160k Jul 2025: 173k Aug 2025: 163k Sep 2025: 171k Oct 2025: 177k Nov 2025: 167k Dec 2025: 186k Jan 2026: 179k Feb 2026: 167k Mar 2026: 184k Apr 2026: 183k May 2026: 181k Jun 2026: 191k

Source: NHSBSA Prescription Cost Analysis, to June 2026

Eplerenone versus Spironolactone with thiazides, June 2026
Measure Eplerenone Spironolactone with thiazides
Items, June 2026 191,307 1
Items, last 12 months 2,122,250 1
Net ingredient cost, June 2026 £483,479 £372

See the full profile for Eplerenone or Spironolactone with thiazides.