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Independent analysis of NHS open data
PharmaInsight

Estradiol and nomegestrol vs Medroxyprogesterone acetate

National NHS prescribing compared (Prescription Cost Analysis)
Data updated April 2026

Medroxyprogesterone acetate was dispensed 68.7× as often as Estradiol and nomegestrol in April 2026 — 56,397 items versus 821 in England.

821items

Estradiol and nomegestrol · April 2026

NHSBSA Prescription Cost Analysis

56,397items

Medroxyprogesterone acetate · April 2026

NHSBSA Prescription Cost Analysis

Figure 1. Estradiol and nomegestrol versus Medroxyprogesterone acetate: national items dispensed by month

▬ Estradiol and nomegestrol   ·   ╌ Medroxyprogesterone acetate

0 36k 73k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 Apr 2026 Medroxyprogester… 821 Jan 2021: 77 Feb 2021: 97 Mar 2021: 104 Apr 2021: 105 May 2021: 117 Jun 2021: 171 Jul 2021: 188 Aug 2021: 227 Sep 2021: 245 Oct 2021: 282 Nov 2021: 329 Dec 2021: 337 Jan 2022: 345 Feb 2022: 349 Mar 2022: 340 Apr 2022: 319 May 2022: 341 Jun 2022: 374 Jul 2022: 340 Aug 2022: 328 Sep 2022: 325 Oct 2022: 368 Nov 2022: 360 Dec 2022: 346 Jan 2023: 354 Feb 2023: 318 Mar 2023: 411 Apr 2023: 331 May 2023: 388 Jun 2023: 421 Jul 2023: 392 Aug 2023: 393 Sep 2023: 423 Oct 2023: 443 Nov 2023: 442 Dec 2023: 411 Jan 2024: 449 Feb 2024: 417 Mar 2024: 445 Apr 2024: 471 May 2024: 482 Jun 2024: 486 Jul 2024: 515 Aug 2024: 443 Sep 2024: 516 Oct 2024: 545 Nov 2024: 515 Dec 2024: 583 Jan 2025: 567 Feb 2025: 539 Mar 2025: 600 Apr 2025: 552 May 2025: 673 Jun 2025: 646 Jul 2025: 755 Aug 2025: 719 Sep 2025: 739 Oct 2025: 798 Nov 2025: 791 Dec 2025: 838 Jan 2026: 886 Feb 2026: 782 Mar 2026: 859 Apr 2026: 821

Source: NHSBSA Prescription Cost Analysis, to April 2026

Estradiol and nomegestrol versus Medroxyprogesterone acetate, April 2026
Measure Estradiol and nomegestrol Medroxyprogesterone acetate
Items, April 2026 821 56,397
Items, last 12 months 9,307 727,099
Net ingredient cost, April 2026 £20,564 £365,279

See the full profile for Estradiol and nomegestrol or Medroxyprogesterone acetate.