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Independent analysis of NHS open data
PharmaInsight

Estriol vs Ospemifene

National NHS prescribing compared (Prescription Cost Analysis)
Data updated May 2026

Estriol was dispensed 625.2× as often as Ospemifene in May 2026 — 174,438 items versus 279 in England.

174,438items

Estriol · May 2026

NHSBSA Prescription Cost Analysis

279items

Ospemifene · May 2026

NHSBSA Prescription Cost Analysis

Figure 1. Estriol versus Ospemifene: national items dispensed by month

▬ Estriol   ·   ╌ Ospemifene

0 88k 177k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 May 2026 Ospemifene 174,438 Jan 2021: 56k Feb 2021: 54k Mar 2021: 62k Apr 2021: 60k May 2021: 61k Jun 2021: 65k Jul 2021: 66k Aug 2021: 64k Sep 2021: 69k Oct 2021: 68k Nov 2021: 72k Dec 2021: 74k Jan 2022: 71k Feb 2022: 73k Mar 2022: 82k Apr 2022: 74k May 2022: 82k Jun 2022: 79k Jul 2022: 80k Aug 2022: 88k Sep 2022: 86k Oct 2022: 88k Nov 2022: 93k Dec 2022: 90k Jan 2023: 91k Feb 2023: 87k Mar 2023: 102k Apr 2023: 88k May 2023: 97k Jun 2023: 97k Jul 2023: 102k Aug 2023: 103k Sep 2023: 102k Oct 2023: 105k Nov 2023: 108k Dec 2023: 105k Jan 2024: 113k Feb 2024: 106k Mar 2024: 102k Apr 2024: 113k May 2024: 120k Jun 2024: 112k Jul 2024: 122k Aug 2024: 120k Sep 2024: 118k Oct 2024: 128k Nov 2024: 125k Dec 2024: 124k Jan 2025: 131k Feb 2025: 121k Mar 2025: 130k Apr 2025: 129k May 2025: 140k Jun 2025: 138k Jul 2025: 150k Aug 2025: 142k Sep 2025: 152k Oct 2025: 163k Nov 2025: 155k Dec 2025: 169k Jan 2026: 168k Feb 2026: 159k Mar 2026: 177k Apr 2026: 174k May 2026: 174k

Source: NHSBSA Prescription Cost Analysis, to May 2026

Estriol versus Ospemifene, May 2026
Measure Estriol Ospemifene
Items, May 2026 174,438 279
Items, last 12 months 1,921,569 2,765
Net ingredient cost, May 2026 £2,779,757 £11,914

See the full profile for Estriol or Ospemifene.