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PharmaInsight

Methylphenidate hydrochloride vs Guanfacine

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Methylphenidate hydrochloride was dispensed 18.2× as often as Guanfacine in March 2026 — 219,736 items versus 12,057 in England.

219,736items

Methylphenidate hydrochloride · March 2026

NHSBSA Prescription Cost Analysis

12,057items

Guanfacine · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Methylphenidate hydrochloride versus Guanfacine: national items dispensed by month

▬ Methylphenidate hydrochloride   ·   ╌ Guanfacine

Guanfacine 219,736

Source: NHSBSA Prescription Cost Analysis, to March 2026

Methylphenidate hydrochloride versus Guanfacine, March 2026
Measure Methylphenidate hydrochloride Guanfacine
Items, March 2026 219,736 12,057
Items, last 12 months 2,280,373 130,551
Net ingredient cost, March 2026 £6,705,510 £876,505

See the full profile for Methylphenidate hydrochloride or Guanfacine.