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Independent analysis of NHS open data
PharmaInsight

Methylprednisolone vs Prednisolone

National NHS prescribing compared (Prescription Cost Analysis)
Data updated May 2026

Prednisolone was dispensed 1,517.2× as often as Methylprednisolone in May 2026 — 461,218 items versus 304 in England.

304items

Methylprednisolone · May 2026

NHSBSA Prescription Cost Analysis

461,218items

Prednisolone · May 2026

NHSBSA Prescription Cost Analysis

Figure 1. Methylprednisolone versus Prednisolone: national items dispensed by month

▬ Methylprednisolone   ·   ╌ Prednisolone

0 393k 786k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 May 2026 Prednisolone 304 Jan 2021: 439 Feb 2021: 413 Mar 2021: 461 Apr 2021: 413 May 2021: 400 Jun 2021: 426 Jul 2021: 440 Aug 2021: 419 Sep 2021: 429 Oct 2021: 401 Nov 2021: 374 Dec 2021: 378 Jan 2022: 421 Feb 2022: 379 Mar 2022: 419 Apr 2022: 389 May 2022: 422 Jun 2022: 422 Jul 2022: 406 Aug 2022: 411 Sep 2022: 338 Oct 2022: 377 Nov 2022: 347 Dec 2022: 390 Jan 2023: 311 Feb 2023: 299 Mar 2023: 439 Apr 2023: 364 May 2023: 389 Jun 2023: 386 Jul 2023: 361 Aug 2023: 361 Sep 2023: 353 Oct 2023: 351 Nov 2023: 326 Dec 2023: 310 Jan 2024: 311 Feb 2024: 350 Mar 2024: 334 Apr 2024: 321 May 2024: 313 Jun 2024: 241 Jul 2024: 303 Aug 2024: 277 Sep 2024: 309 Oct 2024: 328 Nov 2024: 327 Dec 2024: 326 Jan 2025: 315 Feb 2025: 275 Mar 2025: 320 Apr 2025: 322 May 2025: 334 Jun 2025: 295 Jul 2025: 348 Aug 2025: 326 Sep 2025: 320 Oct 2025: 320 Nov 2025: 280 Dec 2025: 317 Jan 2026: 259 Feb 2026: 282 Mar 2026: 286 Apr 2026: 290 May 2026: 304

Source: NHSBSA Prescription Cost Analysis, to May 2026

Methylprednisolone versus Prednisolone, May 2026
Measure Methylprednisolone Prednisolone
Items, May 2026 304 461,218
Items, last 12 months 3,627 6,074,582
Net ingredient cost, May 2026 £8,937 £1,189,633

See the full profile for Methylprednisolone or Prednisolone.