Metolazone vs Spironolactone
National NHS prescribing compared (Prescription Cost Analysis)
Spironolactone was dispensed 238.7× as often as Metolazone in May 2026 — 359,260 items versus 1,505 in England.
1,505items
Metolazone · May 2026
NHSBSA Prescription Cost Analysis
359,260items
Spironolactone · May 2026
NHSBSA Prescription Cost Analysis
Figure 1. Metolazone versus Spironolactone: national items dispensed by month
▬ Metolazone · ╌ Spironolactone
Source: NHSBSA Prescription Cost Analysis, to May 2026
| Measure | Metolazone | Spironolactone |
|---|---|---|
| Items, May 2026 | 1,505 | 359,260 |
| Items, last 12 months | 17,474 | 4,235,084 |
| Net ingredient cost, May 2026 | £90,270 | £1,236,422 |
See the full profile for Metolazone or Spironolactone.