Phenoxymethylpenicillin (Penicillin V) vs Rifaximin

National NHS prescribing compared (Prescription Cost Analysis)

Data updated March 2026

Phenoxymethylpenicillin (Penicillin V) was dispensed 26.4× as often as Rifaximin in March 2026 — 316,146 items versus 11,972 in England.

316,146items

Phenoxymethylpenicillin (Penicillin V) · March 2026

NHSBSA Prescription Cost Analysis

11,972items

Rifaximin · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Phenoxymethylpenicillin (Penicillin V) versus Rifaximin: national items dispensed by month

▬ Phenoxymethylpenicillin (Penicillin V) · ╌ Rifaximin

Source: NHSBSA Prescription Cost Analysis, to March 2026

Phenoxymethylpenicillin (Penicillin V) versus Rifaximin, March 2026
Measure	Phenoxymethylpenicillin (Penicillin V)	Rifaximin
Items, March 2026	316,146	11,972
Items, last 12 months	2,981,784	137,031
Net ingredient cost, March 2026	£659,506	£2,160,163