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Independent analysis of NHS open data
PharmaInsight

Rupatadine fumarate vs Fexofenadine hydrochloride

National NHS prescribing compared (Prescription Cost Analysis)
Data updated June 2026

Fexofenadine hydrochloride was dispensed 3,611.7× as often as Rupatadine fumarate in June 2026 — 783,732 items versus 217 in England.

217items

Rupatadine fumarate · June 2026

NHSBSA Prescription Cost Analysis

783,732items

Fexofenadine hydrochloride · June 2026

NHSBSA Prescription Cost Analysis

Figure 1. Rupatadine fumarate versus Fexofenadine hydrochloride: national items dispensed by month

▬ Rupatadine fumarate   ·   ╌ Fexofenadine hydrochloride

0 392k 784k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 Jun 2026 Fexofenadine hyd… 217 Jan 2021: 158 Feb 2021: 169 Mar 2021: 199 Apr 2021: 189 May 2021: 191 Jun 2021: 244 Jul 2021: 225 Aug 2021: 196 Sep 2021: 216 Oct 2021: 209 Nov 2021: 215 Dec 2021: 199 Jan 2022: 201 Feb 2022: 209 Mar 2022: 208 Apr 2022: 199 May 2022: 206 Jun 2022: 214 Jul 2022: 224 Aug 2022: 206 Sep 2022: 204 Oct 2022: 197 Nov 2022: 197 Dec 2022: 205 Jan 2023: 181 Feb 2023: 175 Mar 2023: 204 Apr 2023: 209 May 2023: 192 Jun 2023: 223 Jul 2023: 199 Aug 2023: 189 Sep 2023: 200 Oct 2023: 191 Nov 2023: 188 Dec 2023: 218 Jan 2024: 197 Feb 2024: 211 Mar 2024: 220 Apr 2024: 211 May 2024: 177 Jun 2024: 243 Jul 2024: 212 Aug 2024: 187 Sep 2024: 179 Oct 2024: 209 Nov 2024: 199 Dec 2024: 200 Jan 2025: 194 Feb 2025: 168 Mar 2025: 205 Apr 2025: 226 May 2025: 221 Jun 2025: 197 Jul 2025: 232 Aug 2025: 190 Sep 2025: 211 Oct 2025: 193 Nov 2025: 192 Dec 2025: 185 Jan 2026: 194 Feb 2026: 176 Mar 2026: 207 Apr 2026: 220 May 2026: 210 Jun 2026: 217

Source: NHSBSA Prescription Cost Analysis, to June 2026

Rupatadine fumarate versus Fexofenadine hydrochloride, June 2026
Measure Rupatadine fumarate Fexofenadine hydrochloride
Items, June 2026 217 783,732
Items, last 12 months 2,427 7,188,922
Net ingredient cost, June 2026 £28,566 £3,018,300

See the full profile for Rupatadine fumarate or Fexofenadine hydrochloride.