Spironolactone vs Co-amilozide (Amiloride hydrochloride/hydrochlorothiazide)

National NHS prescribing compared (Prescription Cost Analysis)

Data updated May 2026

Spironolactone was dispensed 131.7× as often as Co-amilozide (Amiloride hydrochloride/hydrochlorothiazide) in May 2026 — 359,260 items versus 2,727 in England.

359,260items

Spironolactone · May 2026

NHSBSA Prescription Cost Analysis

2,727items

Co-amilozide (Amiloride hydrochloride/hydrochlorothiazide) · May 2026

NHSBSA Prescription Cost Analysis

Figure 1. Spironolactone versus Co-amilozide (Amiloride hydrochloride/hydrochlorothiazide): national items dispensed by month

▬ Spironolactone · ╌ Co-amilozide (Amiloride hydrochloride/hydrochlorothiazide)

Source: NHSBSA Prescription Cost Analysis, to May 2026

Spironolactone versus Co-amilozide (Amiloride hydrochloride/hydrochlorothiazide), May 2026
Measure	Spironolactone	Co-amilozide (Amiloride hydrochloride/hydrochlorothiazide)
Items, May 2026	359,260	2,727
Items, last 12 months	4,235,084	36,149
Net ingredient cost, May 2026	£1,236,422	£124,915

See the full profile for Spironolactone or Co-amilozide (Amiloride hydrochloride/hydrochlorothiazide).