Spironolactone vs Eplerenone
National NHS prescribing compared (Prescription Cost Analysis)
Spironolactone was dispensed 2.0× as often as Eplerenone in March 2026 — 367,450 items versus 183,985 in England.
367,450items
Spironolactone · March 2026
NHSBSA Prescription Cost Analysis
183,985items
Eplerenone · March 2026
NHSBSA Prescription Cost Analysis
Figure 1. Spironolactone versus Eplerenone: national items dispensed by month
▬ Spironolactone · ╌ Eplerenone
Source: NHSBSA Prescription Cost Analysis, to March 2026
| Measure | Spironolactone | Eplerenone |
|---|---|---|
| Items, March 2026 | 367,450 | 183,985 |
| Items, last 12 months | 4,181,506 | 2,047,274 |
| Net ingredient cost, March 2026 | £1,253,634 | £396,187 |
See the full profile for Spironolactone or Eplerenone.