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Independent analysis of NHS open data
PharmaInsight

Tenofovir disoproxil vs Entecavir

National NHS prescribing compared (Prescription Cost Analysis)
Data updated May 2026

Entecavir was dispensed 2.5× as often as Tenofovir disoproxil in May 2026 — 279 items versus 111 in England.

111items

Tenofovir disoproxil · May 2026

NHSBSA Prescription Cost Analysis

279items

Entecavir · May 2026

NHSBSA Prescription Cost Analysis

Figure 1. Tenofovir disoproxil versus Entecavir: national items dispensed by month

▬ Tenofovir disoproxil   ·   ╌ Entecavir

0 150 300 Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Apr 2025 May 2026 Entecavir 111 Jan 2021: 184 Feb 2021: 175 Mar 2021: 183 Apr 2021: 174 May 2021: 180 Jun 2021: 168 Jul 2021: 175 Aug 2021: 181 Sep 2021: 187 Oct 2021: 176 Nov 2021: 186 Dec 2021: 182 Jan 2022: 192 Feb 2022: 169 Mar 2022: 213 Apr 2022: 202 May 2022: 184 Jun 2022: 197 Jul 2022: 190 Aug 2022: 196 Sep 2022: 188 Oct 2022: 193 Nov 2022: 176 Dec 2022: 152 Jan 2023: 175 Feb 2023: 159 Mar 2023: 159 Apr 2023: 151 May 2023: 159 Jun 2023: 170 Jul 2023: 158 Aug 2023: 135 Sep 2023: 165 Oct 2023: 145 Nov 2023: 156 Dec 2023: 142 Jan 2024: 172 Feb 2024: 159 Mar 2024: 168 Apr 2024: 139 May 2024: 111 Jun 2024: 120 Jul 2024: 120 Aug 2024: 137 Oct 2024: 116 Nov 2024: 126 Dec 2024: 129 Jan 2025: 128 Feb 2025: 128 Mar 2025: 129 Apr 2025: 117 May 2025: 103 Jun 2025: 94 Jul 2025: 112 Aug 2025: 95 Sep 2025: 97 Oct 2025: 106 Nov 2025: 128 Dec 2025: 113 Jan 2026: 135 Feb 2026: 114 Mar 2026: 128 Apr 2026: 115 May 2026: 111

Source: NHSBSA Prescription Cost Analysis, to May 2026

Tenofovir disoproxil versus Entecavir, May 2026
Measure Tenofovir disoproxil Entecavir
Items, May 2026 111 279
Items, last 12 months 1,348 3,325
Net ingredient cost, May 2026 £9,431 £138,668

See the full profile for Tenofovir disoproxil or Entecavir.