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Independent analysis of NHS open data
PharmaInsight

Trimethoprim vs Nitrofurantoin

National NHS prescribing compared (Prescription Cost Analysis)
Data updated May 2026

Nitrofurantoin was dispensed 2.8× as often as Trimethoprim in May 2026 — 333,741 items versus 119,157 in England.

119,157items

Trimethoprim · May 2026

NHSBSA Prescription Cost Analysis

333,741items

Nitrofurantoin · May 2026

NHSBSA Prescription Cost Analysis

Figure 1. Trimethoprim versus Nitrofurantoin: national items dispensed by month

▬ Trimethoprim   ·   ╌ Nitrofurantoin

0 204k 408k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 May 2026 Nitrofurantoin 119,157 Jan 2021: 125k Feb 2021: 116k Mar 2021: 130k Apr 2021: 118k May 2021: 116k Jun 2021: 122k Jul 2021: 126k Aug 2021: 123k Sep 2021: 130k Oct 2021: 127k Nov 2021: 131k Dec 2021: 132k Jan 2022: 129k Feb 2022: 121k Mar 2022: 133k Apr 2022: 119k May 2022: 128k Jun 2022: 122k Jul 2022: 122k Aug 2022: 127k Sep 2022: 131k Oct 2022: 130k Nov 2022: 136k Dec 2022: 128k Jan 2023: 135k Feb 2023: 126k Mar 2023: 138k Apr 2023: 118k May 2023: 126k Jun 2023: 127k Jul 2023: 129k Aug 2023: 132k Sep 2023: 132k Oct 2023: 135k Nov 2023: 135k Dec 2023: 131k Jan 2024: 139k Feb 2024: 131k Mar 2024: 132k Apr 2024: 133k May 2024: 134k Jun 2024: 126k Jul 2024: 137k Aug 2024: 130k Sep 2024: 135k Oct 2024: 142k Nov 2024: 135k Dec 2024: 135k Jan 2025: 139k Feb 2025: 124k Mar 2025: 129k Apr 2025: 123k May 2025: 127k Jun 2025: 125k Jul 2025: 136k Aug 2025: 126k Sep 2025: 137k Oct 2025: 141k Nov 2025: 130k Dec 2025: 138k Jan 2026: 133k Feb 2026: 122k Mar 2026: 132k Apr 2026: 122k May 2026: 119k

Source: NHSBSA Prescription Cost Analysis, to May 2026

Trimethoprim versus Nitrofurantoin, May 2026
Measure Trimethoprim Nitrofurantoin
Items, May 2026 119,157 333,741
Items, last 12 months 1,561,883 4,416,505
Net ingredient cost, May 2026 £591,028 £2,268,636

See the full profile for Trimethoprim or Nitrofurantoin.