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Independent analysis of NHS open data
PharmaInsight

Asfotase alfa 80mg/0.8ml solution for injection vials

Secondary Care Medicines Data (SCMD) · indicative cost
Data updated April 2026

NHS hospitals in England used £51,170,112 of indicative cost of Asfotase alfa 80mg/0.8ml solution for injection vials in the 12 months to April 2026, about 0.2% of all hospital medicines spend. That is up 7.8% on the previous 12 months.

£51,170,112 +7.8%

Indicative cost · 12 months

8,702units

Quantity (VMP units) · 12 months

0.2%

Share of hospital medicines spend

Figure 1. Asfotase alfa 80mg/0.8ml solution for injection vials: NHS hospital indicative cost by month (£ millions)

£0m £10.1m £20.3m Apr 2021 Jan 2022 Oct 2022 Jul 2023 Apr 2024 Jan 2025 Apr 2026 £3.6m Apr 2021: £13.3m May 2021: £7.1m Jun 2021: £12.6m Jul 2021: £10.4m Aug 2021: £9.1m Sep 2021: £12.7m Oct 2021: £15.1m Nov 2021: £11.7m Dec 2021: £13.8m Jan 2022: £13.9m Feb 2022: £9.4m Mar 2022: £14.2m Apr 2022: £13.1m May 2022: £11.6m Jun 2022: £3.9m Jul 2022: £20.3m Aug 2022: £18.0m Sep 2022: £9.1m Oct 2022: £1.8m Nov 2022: £18.4m Dec 2022: £2.4m Jan 2023: £4.6m Feb 2023: £1.1m Mar 2023: £2.3m Apr 2023: £3.9m May 2023: £2.1m Jun 2023: £3.1m Jul 2023: £2.6m Aug 2023: £2.8m Sep 2023: £3.7m Oct 2023: £2.8m Nov 2023: £3.4m Dec 2023: £3.4m Jan 2024: £2.8m Feb 2024: £2.9m Mar 2024: £5.6m Apr 2024: £3.5m May 2024: £4.3m Jun 2024: £3.0m Jul 2024: £5.3m Aug 2024: £4.5m Sep 2024: £2.9m Oct 2024: £4.8m Nov 2024: £3.2m Dec 2024: £4.8m Jan 2025: £4.2m Feb 2025: £4.0m Mar 2025: £2.3m Apr 2025: £4.2m May 2025: £4.1m Jun 2025: £3.9m Jul 2025: £3.7m Aug 2025: £4.5m Sep 2025: £4.2m Oct 2025: £5.8m Nov 2025: £3.8m Dec 2025: £4.7m Jan 2026: £5.1m Feb 2026: £3.2m Mar 2026: £4.7m Apr 2026: £3.6m

Source: NHSBSA Secondary Care Medicines Data, to April 2026

Cost is indicative — actual hospital medicine prices are commercially confidential, so these figures are estimated from list prices. See methodology.

NHS trusts using Asfotase alfa 80mg/0.8ml solution for injection vials most

By indicative cost over the 12 months to April 2026.

NHS trusts using Asfotase alfa 80mg/0.8ml solution for injection vials most, by indicative cost
NHS trustIndicative cost (12 months)
St George's Univ Hosps Foundation Nhst £19,079,424
Sheffield Teaching Hospitals Nhs Trust £17,273,088
Royal National Ortho.hospital Trust £6,999,552
Manchester University Nhs Ft £3,612,672
Sheffield Children's Nhs Ft £1,994,496
Cambridge Univ Hosp Nhs Foundation Trust £1,251,264
Oxford University Hospitals Nhs Ft £903,168
Birmingham Womans & Childrens Nhs Ft £56,448

The primary-care picture

Asfotase alfa is also dispensed in the community. See the national primary-care prescribing volume, cost and trend on the Asfotase alfa medicine page.