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Independent analysis of NHS open data
PharmaInsight

C1-esterase inhibitor human 500unit powder and solvent for solution for injection vials

Secondary Care Medicines Data (SCMD) · indicative cost
Data updated April 2026

NHS hospitals in England used £16,676,300 of indicative cost of C1-esterase inhibitor human 500unit powder and solvent for solution for injection vials in the 12 months to April 2026, about 0.1% of all hospital medicines spend. That is down 82.7% on the previous 12 months.

£16,676,300 -82.7%

Indicative cost · 12 months

24,890units

Quantity (VMP units) · 12 months

0.1%

Share of hospital medicines spend

Figure 1. C1-esterase inhibitor human 500unit powder and solvent for solution for injection vials: NHS hospital indicative cost by month (£ millions)

£0m £14.5m £28.9m Mar 2024 Jul 2024 Nov 2024 Mar 2025 Jul 2025 Nov 2025 Apr 2026 £0.6m Mar 2024: £1.6m Apr 2024: £27.7m May 2024: £1.9m Jun 2024: £14.8m Jul 2024: £12.9m Aug 2024: £3.6m Sep 2024: £28.9m Oct 2024: £2.2m Nov 2024: £3.4m Dec 2024: £13.5m Jan 2025: £12.9m Feb 2025: £0.7m Mar 2025: £0.9m Apr 2025: £0.7m May 2025: £0.6m Jun 2025: £1.0m Jul 2025: £0.9m Aug 2025: £0.7m Sep 2025: £8.8m Oct 2025: £0.9m Nov 2025: £0.6m Dec 2025: £0.6m Jan 2026: £0.6m Feb 2026: £0.8m Mar 2026: £0.7m Apr 2026: £0.6m

Source: NHSBSA Secondary Care Medicines Data, to April 2026

Cost is indicative — actual hospital medicine prices are commercially confidential, so these figures are estimated from list prices. See methodology.

NHS trusts using C1-esterase inhibitor human 500unit powder and solvent for solution for injection vials most

By indicative cost over the 12 months to April 2026.

NHS trusts using C1-esterase inhibitor human 500unit powder and solvent for solution for injection vials most, by indicative cost
NHS trustIndicative cost (12 months)
Univ Hpl B/Ham Nhs Foundation Trust £8,294,600
Barts Health Nhs Trust £1,079,370
Aintree University Hospital Nhs Ft £884,400
Manchester University Nhs Ft £772,510
Frimley Health Nhs Foundation Trust £719,580
Sandwell And West Birmingham Hpls Trust £531,310
Leeds Teaching Hpls Nhs Trust £460,960
Cambridge Univ Hosp Nhs Foundation Trust £423,440
Western Sussex Hospitals Nhs Found Trust £412,050
North Bristol Nhs Trust £334,330

The primary-care picture

No confident match to a community-dispensed medicine was found for this product, so no primary-care comparison is shown. SCMD products are recorded at product level, which does not always map cleanly to a BNF substance.