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Independent analysis of NHS open data
PharmaInsight

Sapropterin 100mg soluble tablets sugar free

Secondary Care Medicines Data (SCMD) · indicative cost
Data updated July 2026

NHS hospitals in England used £18,522,089 of indicative cost of Sapropterin 100mg soluble tablets sugar free in the 12 months to July 2026, about 0.1% of all hospital medicines spend. That is down 1.0% on the previous 12 months.

£18,522,089 -1%

Indicative cost · 12 months

840,327units

Quantity (VMP units) · 12 months

0.1%

Share of hospital medicines spend

Figure 1. Sapropterin 100mg soluble tablets sugar free: NHS hospital indicative cost by month (£ millions)

£0m £6.8m £13.6m Apr 2021 Feb 2022 Dec 2022 Oct 2023 Aug 2024 Jun 2025 Jul 2026 £1.8m Apr 2021: £0.2m May 2021: £0.1m Jun 2021: £0.3m Jul 2021: £0.1m Aug 2021: £0.1m Sep 2021: £0.2m Oct 2021: £0.4m Nov 2021: £0.1m Dec 2021: £0.2m Jan 2022: £0.2m Feb 2022: £0.3m Mar 2022: £0.4m Apr 2022: £0.3m May 2022: £0.5m Jun 2022: £0.9m Jul 2022: £1.8m Aug 2022: £0.6m Sep 2022: £0.6m Oct 2022: £3.5m Nov 2022: £1.1m Dec 2022: £0.8m Jan 2023: £1.5m Feb 2023: £1.0m Mar 2023: £1.6m Apr 2023: £1.1m May 2023: £1.4m Jun 2023: £1.7m Jul 2023: £1.9m Aug 2023: £13.6m Sep 2023: £12.9m Oct 2023: £4.6m Nov 2023: £1.3m Dec 2023: £1.3m Jan 2024: £1.3m Feb 2024: £2.3m Mar 2024: £1.0m Apr 2024: £1.4m May 2024: £1.2m Jun 2024: £1.4m Jul 2024: £1.5m Aug 2024: £1.6m Sep 2024: £1.6m Oct 2024: £1.7m Nov 2024: £1.6m Dec 2024: £1.4m Jan 2025: £1.3m Feb 2025: £1.7m Mar 2025: £1.4m Apr 2025: £1.6m May 2025: £1.7m Jun 2025: £1.0m Jul 2025: £2.1m Aug 2025: £1.2m Sep 2025: £1.2m Oct 2025: £1.8m Nov 2025: £1.7m Dec 2025: £1.2m Jan 2026: £1.9m Feb 2026: £1.5m Mar 2026: £1.8m Apr 2026: £1.3m May 2026: £1.4m Jun 2026: £1.7m Jul 2026: £1.8m

Source: NHSBSA Secondary Care Medicines Data, to July 2026

Cost is indicative — actual hospital medicine prices are commercially confidential, so these figures are estimated from list prices. See methodology.

NHS trusts using Sapropterin 100mg soluble tablets sugar free most

By indicative cost over the 12 months to July 2026.

NHS trusts using Sapropterin 100mg soluble tablets sugar free most, by indicative cost
NHS trustIndicative cost (12 months)
University College London Foundation Tr £3,338,950
Guy's & St Thomas' Nhs Foundation Trust £3,216,113
Salford Royal Nhs Foundation Trust £2,132,800
Manchester University Nhs Ft £1,486,510
The Newcastle Upon Tyne Hpl Nhs Found Tr £1,208,838
Sheffield Teaching Hospitals Nhs Trust £1,042,374
Univ Hpls Bristol Nhs Foundation Trust £1,020,175
Sheffield Children's Nhs Ft £1,016,950
Alder Hey Childrens Nhs Foundation Trust £816,104
North Bristol Nhs Trust £748,200

The primary-care picture

Sapropterin is also dispensed in the community. See the national primary-care prescribing volume, cost and trend on the Sapropterin medicine page.