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Independent analysis of NHS open data
PharmaInsight

Esomeprazole

Gastro-Intestinal System Antisecretory drugs and mucosal protectants BNF 0103050E0
Data updated May 2026 Download CSV

Esomeprazole was ranked 105th of 1,796 medicines by items in May 2026, with 237,099 items, down 3.4% on a year earlier.

237,099items -3.4%

Dispensed in May 2026

2,419,895items

Rolling 12 months

£1,037,804

Net ingredient cost · May 2026

Figure 1. Esomeprazole: national items dispensed by month

0 129k 258k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 Jul 2026 254,118 Jan 2021: 202k Feb 2021: 189k Mar 2021: 212k Apr 2021: 204k May 2021: 196k Jun 2021: 209k Jul 2021: 209k Aug 2021: 200k Sep 2021: 211k Oct 2021: 202k Nov 2021: 210k Dec 2021: 223k Jan 2022: 210k Feb 2022: 196k Mar 2022: 222k Apr 2022: 209k May 2022: 220k Jun 2022: 214k Jul 2022: 214k Aug 2022: 221k Sep 2022: 219k Oct 2022: 218k Nov 2022: 223k Dec 2022: 226k Jan 2023: 225k Feb 2023: 205k Mar 2023: 237k Apr 2023: 212k May 2023: 227k Jun 2023: 231k Jul 2023: 226k Aug 2023: 230k Sep 2023: 226k Oct 2023: 229k Nov 2023: 230k Dec 2023: 232k Jan 2024: 237k Feb 2024: 223k Mar 2024: 225k Apr 2024: 236k May 2024: 239k Jun 2024: 225k Jul 2024: 244k Aug 2024: 236k Sep 2024: 231k Oct 2024: 245k Nov 2024: 234k Dec 2024: 243k Jan 2025: 247k Feb 2025: 220k Mar 2025: 235k Apr 2025: 236k May 2025: 245k Jun 2025: 236k Jul 2025: 253k Aug 2025: 232k Sep 2025: 247k Oct 2025: 253k Nov 2025: 231k Dec 2025: 258k Jan 2026: 246k Feb 2026: 225k Mar 2026: 247k Apr 2026: 242k May 2026: 237k Jun 2026: 246k Jul 2026: 254k

Source: NHSBSA Prescription Cost Analysis, to May 2026

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At a glance

  • Therapeutic class Antisecretory drugs and mucosal protectants
  • Presentations 15 shown
  • Average cost / item £4.38
  • Year on year Down 3.4% on a year earlier
What this is
Net ingredient cost is the list price before discounts and dispensing fees, not what the NHS finally pays.

Top presentations, May 2026

The individual products dispensed under Esomeprazole this month.

Presentations of Esomeprazole, May 2026
Presentation BNF code Items Net ingredient cost
Esomeprazole 20mg gastro-resistant capsules 0103050E0AAAFAF 92,828 £324,174
Esomeprazole 40mg gastro-resistant capsules 0103050E0AAAGAG 61,022 £199,188
Esomeprazole 20mg gastro-resistant tablets 0103050E0AAAAAA 45,210 £173,708
Esomeprazole 40mg gastro-resistant tablets 0103050E0AAABAB 31,808 £116,139
Nexium 20mg gastro-resistant tablets (AstraZeneca) 0103050E0BBAAAA 2,429 £76,689
Nexium 40mg gastro-resistant tablets (AstraZeneca) 0103050E0BBABAB 1,569 £54,989
Esomeprazole 10mg gastro-resistant granules sachets 0103050E0AAAEAE 970 £74,562
Emozul 20mg gastro-resistant capsules 0103050E0BCAAAF 623 £5,358
Emozul 40mg gastro-resistant capsules 0103050E0BCABAG 433 £3,793
Nexium 10mg gastro-resistant granules sachets 0103050E0BBADAE 103 £6,852
Nexium Control 20mg gastro-resistant tablets 0103050E0BBAGAA 33 £799
Ventra 20mg gastro-resistant capsules 0103050E0BDAAAF 31 £133
Ventra 40mg gastro-resistant capsules 0103050E0BDABAG 22 £87
Nexium Control 20mg gastro-resistant capsules 0103050E0BBAHAF 16 £431
Esomeprazole 40mg/5ml oral suspension 0103050E0AAADAD 1 £775

Source: NHSBSA Prescription Cost Analysis · to May 2026 OGL v3.0

Where Esomeprazole is dispensed

The regions and dispensing practices with the highest Esomeprazole volumes.

Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.

Compare Esomeprazole with

Other medicines in the same BNF section, by prescribing volume.

Download this data

The monthly series for Esomeprazole is in this page's CSV. For the ranked national series across every medicine, with the method and caveats documented, see the most-prescribed medicines dataset in our open data catalogue.