Medicines
Gastro-Intestinal System
Antisecretory drugs and mucosal protectants
Esomeprazole

Esomeprazole

Gastro-Intestinal System Antisecretory drugs and mucosal protectants BNF 0103050E0

Data updated April 2026 Download CSV

Esomeprazole was ranked 106th of 1,792 medicines by items in April 2026, with 242,387 items, up 2.7% on a year earlier.

242,387items +2.7%

Dispensed in April 2026

2,671,419items

Rolling 12 months

£1,067,730

Net ingredient cost · April 2026

Figure 1. Esomeprazole: national items dispensed by month

Source: NHSBSA Prescription Cost Analysis, to April 2026

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<iframe src="https://pharmainsight.co.uk/embed/medicines/esomeprazole-0103050e0" width="100%" height="280" style="border:0" loading="lazy" title="Esomeprazole: NHS prescribing in England — PharmaInsight"></iframe>

At a glance

Therapeutic class Antisecretory drugs and mucosal protectants
Presentations 15 shown
Average cost / item £4.41
Year on year Up 2.7% on a year earlier

What this is

Net ingredient cost is the list price before discounts and dispensing fees, not what the NHS finally pays.

Top presentations, April 2026

The individual products dispensed under Esomeprazole this month.

Presentations of Esomeprazole, April 2026
Presentation	BNF code	Items	Net ingredient cost
Esomeprazole 20mg gastro-resistant capsules	0103050E0AAAFAF	94,248	£326,946
Esomeprazole 40mg gastro-resistant capsules	0103050E0AAAGAG	62,386	£203,108
Esomeprazole 20mg gastro-resistant tablets	0103050E0AAAAAA	46,681	£179,559
Esomeprazole 40mg gastro-resistant tablets	0103050E0AAABAB	32,306	£117,966
Nexium 20mg gastro-resistant tablets (AstraZeneca)	0103050E0BBAAAA	2,641	£82,007
Nexium 40mg gastro-resistant tablets (AstraZeneca)	0103050E0BBABAB	1,734	£62,271
Esomeprazole 10mg gastro-resistant granules sachets	0103050E0AAAEAE	999	£77,104
Emozul 20mg gastro-resistant capsules	0103050E0BCAAAF	646	£5,454
Emozul 40mg gastro-resistant capsules	0103050E0BCABAG	477	£4,212
Nexium 10mg gastro-resistant granules sachets	0103050E0BBADAE	108	£6,776
Ventra 20mg gastro-resistant capsules	0103050E0BDAAAF	71	£319
Ventra 40mg gastro-resistant capsules	0103050E0BDABAG	43	£202
Nexium Control 20mg gastro-resistant tablets	0103050E0BBAGAA	27	£691
Nexium Control 20mg gastro-resistant capsules	0103050E0BBAHAF	13	£182
Nexium I.V 40mg powder for solution for injection vials	0103050E0BBACAC	3	£98

Source: NHSBSA Prescription Cost Analysis · to April 2026 OGL v3.0

Where Esomeprazole is dispensed

The regions and dispensing practices with the highest Esomeprazole volumes.

Top regions

NHS North East and North Cumbria Integrated Care Board 19,923
NHS West Yorkshire Integrated Care Board 17,847
NHS Cheshire and Merseyside Integrated Care Board 13,955
NHS Greater Manchester Integrated Care Board 13,807
NHS Lancashire and South Cumbria Integrated Care Board 10,514

Top dispensing practices

Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.

Compare Esomeprazole with

Other medicines in the same BNF section, by prescribing volume.

Esomeprazole vs Lansoprazole Esomeprazole vs Omeprazole Esomeprazole vs Famotidine Esomeprazole vs Pantoprazole Esomeprazole vs Rabeprazole sodium