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Independent analysis of NHS open data
PharmaInsight

Oxycodone hydrochloride/naloxone hydrochloride

Central Nervous System Analgesics BNF 0407020AF
Data updated May 2026 Download CSV

Oxycodone hydrochloride/naloxone hydrochloride was ranked 799th of 1,796 medicines by items in May 2026, with 1,609 items, down 11.1% on a year earlier.

1,609items -11.1%

Dispensed in May 2026

16,485items

Rolling 12 months

£99,381

Net ingredient cost · May 2026

Figure 1. Oxycodone hydrochloride/naloxone hydrochloride: national items dispensed by month

0 1k 3k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 Jul 2026 2,917 Jan 2021: 3k Feb 2021: 3k Mar 2021: 3k Apr 2021: 3k May 2021: 3k Jun 2021: 3k Jul 2021: 3k Aug 2021: 3k Sep 2021: 3k Oct 2021: 3k Nov 2021: 3k Dec 2021: 3k Jan 2022: 2k Feb 2022: 2k Mar 2022: 3k Apr 2022: 2k May 2022: 3k Jun 2022: 2k Jul 2022: 2k Aug 2022: 2k Sep 2022: 2k Oct 2022: 2k Nov 2022: 2k Dec 2022: 2k Jan 2023: 2k Feb 2023: 2k Mar 2023: 2k Apr 2023: 2k May 2023: 2k Jun 2023: 2k Jul 2023: 2k Aug 2023: 2k Sep 2023: 2k Oct 2023: 2k Nov 2023: 2k Dec 2023: 2k Jan 2024: 2k Feb 2024: 2k Mar 2024: 2k Apr 2024: 2k May 2024: 2k Jun 2024: 2k Jul 2024: 2k Aug 2024: 2k Sep 2024: 2k Oct 2024: 2k Nov 2024: 2k Dec 2024: 2k Jan 2025: 2k Feb 2025: 2k Mar 2025: 2k Apr 2025: 2k May 2025: 2k Jun 2025: 2k Jul 2025: 2k Aug 2025: 2k Sep 2025: 2k Oct 2025: 2k Nov 2025: 2k Dec 2025: 2k Jan 2026: 2k Feb 2026: 1k Mar 2026: 2k Apr 2026: 2k May 2026: 2k Jun 2026: 2k Jul 2026: 3k

Source: NHSBSA Prescription Cost Analysis, to May 2026

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At a glance

  • Therapeutic class Analgesics
  • Presentations 14 shown
  • Average cost / item £61.77
  • Year on year Down 11.1% on a year earlier
What this is
Net ingredient cost is the list price before discounts and dispensing fees, not what the NHS finally pays.

Top presentations, May 2026

The individual products dispensed under Oxycodone hydrochloride/naloxone hydrochloride this month.

Presentations of Oxycodone hydrochloride/naloxone hydrochloride, May 2026
Presentation BNF code Items Net ingredient cost
Targinact 10mg/5mg modified-release tablets 0407020AFBBAAAA 581 £25,873
Targinact 5mg/2.5mg modified-release tablets 0407020AFBBACAC 461 £19,156
Targinact 20mg/10mg modified-release tablets 0407020AFBBABAB 184 £16,799
Oxycodone 20mg / Naloxone 10mg modified-release tablets 0407020AFAAABAB 226 £16,824
Oxycodone 40mg / Naloxone 20mg modified-release tablets 0407020AFAAADAD 71 £9,734
Targinact 40mg/20mg modified-release tablets 0407020AFBBADAD 59 £9,988
Myloxifin 5mg/2.5mg modified-release tablets 0407020AFBCADAC 9 £256
Myloxifin 20mg/10mg modified-release tablets 0407020AFBCABAB 6 £332
Myloxifin 10mg/5mg modified-release tablets 0407020AFBCAAAA 4 £105
Sofonac 10mg/5mg modified-release tablets 0407020AFBEAAAA 3 £51
Sofonac 5mg/2.5mg modified-release tablets 0407020AFBEADAC 2 £42
Myloxifin 40mg/20mg modified-release tablets 0407020AFBCACAD 1 £121
Sofonac 20mg/10mg modified-release tablets 0407020AFBEABAB 1 £34
Sofonac 40mg/20mg modified-release tablets 0407020AFBEACAD 1 £68

Source: NHSBSA Prescription Cost Analysis · to May 2026 OGL v3.0

Where Oxycodone hydrochloride/naloxone hydrochloride is dispensed

The regions and dispensing practices with the highest Oxycodone hydrochloride/naloxone hydrochloride volumes.

Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.

Compare Oxycodone hydrochloride/naloxone hydrochloride with

Other medicines in the same BNF section, by prescribing volume.

Download this data

The monthly series for Oxycodone hydrochloride/naloxone hydrochloride is in this page's CSV. For the ranked national series across every medicine, with the method and caveats documented, see the most-prescribed medicines dataset in our open data catalogue.