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Independent analysis of NHS open data
PharmaInsight

Sacubitril/valsartan

Cardiovascular System Hypertension and heart failure BNF 0205052AE
Data updated May 2026 Download CSV

Sacubitril/valsartan was ranked 130th of 1,796 medicines by items in May 2026, with 167,472 items, up 11.2% on a year earlier.

167,472items +11.2%

Dispensed in May 2026

1,627,474items

Rolling 12 months

£14,286,762

Net ingredient cost · May 2026

Figure 1. Sacubitril/valsartan: national items dispensed by month

0 88k 176k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 Jul 2026 156,490 Jan 2021: 35k Feb 2021: 34k Mar 2021: 40k Apr 2021: 40k May 2021: 40k Jun 2021: 45k Jul 2021: 47k Aug 2021: 47k Sep 2021: 51k Oct 2021: 50k Nov 2021: 54k Dec 2021: 59k Jan 2022: 58k Feb 2022: 56k Mar 2022: 65k Apr 2022: 63k May 2022: 68k Jun 2022: 68k Jul 2022: 70k Aug 2022: 74k Sep 2022: 75k Oct 2022: 77k Nov 2022: 81k Dec 2022: 83k Jan 2023: 85k Feb 2023: 80k Mar 2023: 93k Apr 2023: 86k May 2023: 94k Jun 2023: 98k Jul 2023: 99k Aug 2023: 102k Sep 2023: 103k Oct 2023: 106k Nov 2023: 108k Dec 2023: 111k Jan 2024: 116k Feb 2024: 111k Mar 2024: 115k Apr 2024: 121k May 2024: 126k Jun 2024: 120k Jul 2024: 133k Aug 2024: 130k Sep 2024: 128k Oct 2024: 138k Nov 2024: 135k Dec 2024: 140k Jan 2025: 144k Feb 2025: 131k Mar 2025: 141k Apr 2025: 144k May 2025: 151k Jun 2025: 149k Jul 2025: 161k Aug 2025: 151k Sep 2025: 159k Oct 2025: 165k Nov 2025: 154k Dec 2025: 172k Jan 2026: 166k Feb 2026: 155k Mar 2026: 170k Apr 2026: 169k May 2026: 167k Jun 2026: 176k Jul 2026: 156k

Source: NHSBSA Prescription Cost Analysis, to May 2026

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At a glance

  • Therapeutic class Hypertension and heart failure
  • Presentations 5 shown
  • Average cost / item £85.31
  • Year on year Up 11.2% on a year earlier
What this is
Net ingredient cost is the list price before discounts and dispensing fees, not what the NHS finally pays.

Top presentations, May 2026

The individual products dispensed under Sacubitril/valsartan this month.

Presentations of Sacubitril/valsartan, May 2026
Presentation BNF code Items Net ingredient cost
Entresto 24mg/26mg tablets 0205052AEBBACAC 67,561 £5,404,114
Entresto 97mg/103mg tablets 0205052AEBBABAB 52,078 £4,737,452
Entresto 49mg/51mg tablets 0205052AEBBAAAA 47,724 £4,142,908
Entresto 15mg/16mg granules in capsules for opening 0205052AEBBAEAE 74 £1,799
Entresto 6mg/6mg granules in capsules for opening 0205052AEBBADAD 35 £488

Source: NHSBSA Prescription Cost Analysis · to May 2026 OGL v3.0

Where Sacubitril/valsartan is dispensed

The regions and dispensing practices with the highest Sacubitril/valsartan volumes.

Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.

Compare Sacubitril/valsartan with

Other medicines in the same BNF section, by prescribing volume.

Download this data

The monthly series for Sacubitril/valsartan is in this page's CSV. For the ranked national series across every medicine, with the method and caveats documented, see the most-prescribed medicines dataset in our open data catalogue.