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Independent analysis of NHS open data
PharmaInsight

Aceclofenac vs Methotrexate

National NHS prescribing compared (Prescription Cost Analysis)
Data updated April 2026

Methotrexate was dispensed 860.8× as often as Aceclofenac in April 2026 — 187,649 items versus 218 in England.

218items

Aceclofenac · April 2026

NHSBSA Prescription Cost Analysis

187,649items

Methotrexate · April 2026

NHSBSA Prescription Cost Analysis

Figure 1. Aceclofenac versus Methotrexate: national items dispensed by month

▬ Aceclofenac   ·   ╌ Methotrexate

0 99k 198k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 Apr 2026 Methotrexate 218 Jan 2021: 427 Feb 2021: 392 Mar 2021: 419 Apr 2021: 459 May 2021: 407 Jun 2021: 422 Jul 2021: 432 Aug 2021: 427 Sep 2021: 417 Oct 2021: 387 Nov 2021: 399 Dec 2021: 428 Jan 2022: 400 Feb 2022: 365 Mar 2022: 418 Apr 2022: 400 May 2022: 392 Jun 2022: 407 Jul 2022: 374 Aug 2022: 392 Sep 2022: 380 Oct 2022: 382 Nov 2022: 377 Dec 2022: 370 Jan 2023: 364 Feb 2023: 330 Mar 2023: 390 Apr 2023: 349 May 2023: 371 Jun 2023: 381 Jul 2023: 337 Aug 2023: 366 Sep 2023: 377 Oct 2023: 327 Nov 2023: 375 Dec 2023: 353 Jan 2024: 393 Feb 2024: 323 Mar 2024: 351 Apr 2024: 342 May 2024: 358 Jun 2024: 325 Jul 2024: 357 Aug 2024: 343 Sep 2024: 329 Oct 2024: 361 Nov 2024: 329 Dec 2024: 321 Jan 2025: 331 Feb 2025: 280 Mar 2025: 291 Apr 2025: 303 May 2025: 273 Jun 2025: 269 Jul 2025: 310 Aug 2025: 278 Sep 2025: 292 Oct 2025: 277 Nov 2025: 256 Dec 2025: 255 Jan 2026: 247 Feb 2026: 212 Mar 2026: 228 Apr 2026: 218

Source: NHSBSA Prescription Cost Analysis, to April 2026

Aceclofenac versus Methotrexate, April 2026
Measure Aceclofenac Methotrexate
Items, April 2026 218 187,649
Items, last 12 months 3,115 2,242,345
Net ingredient cost, April 2026 £2,006 £2,311,461

See the full profile for Aceclofenac or Methotrexate.