Methotrexate
National NHS prescribing (Prescription Cost Analysis) · Drugs used in rheumatic diseases and gout
Methotrexate was ranked 123rd of 1,794 medicines by items in March 2026, with 190,005 items, up 5.0% on a year earlier.
190,005items
Dispensed in March 2026
NHSBSA Prescription Cost Analysis
£2,295,534
Net ingredient cost · March 2026
NHSBSA PCA
2,236,642items
Dispensed in the last 12 months
NHSBSA PCA
Figure 1. Methotrexate: national items dispensed by month
Source: NHSBSA Prescription Cost Analysis, to March 2026
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Top presentations, March 2026
The individual products dispensed under Methotrexate, by items this month.
| Presentation | Items | Net ingredient cost |
|---|---|---|
| Methotrexate 2.5mg tablets | 157,847 | £202,508 |
| Metoject PEN 20mg/0.4ml inj pre-filled pens | 9,221 | £618,634 |
| Metoject PEN 15mg/0.3ml inj pre-filled pens | 6,475 | £414,965 |
| Metoject PEN 25mg/0.5ml inj pre-filled pens | 6,211 | £429,655 |
| Metoject PEN 10mg/0.2ml inj pre-filled pens | 2,705 | £158,629 |
| Metoject PEN 17.5mg/0.35ml inj pre-filled pens | 1,755 | £120,536 |
| Metoject PEN 12.5mg/0.25ml inj pre-filled pens | 1,387 | £92,457 |
| Metoject PEN 22.5mg/0.45ml inj pre-filled pens | 935 | £66,840 |
| Metoject PEN 7.5mg/0.15ml inj pre-filled pens | 862 | £49,627 |
| Methofill 20mg/0.4ml inj pre-filled syringes | 371 | £21,951 |
| Methotrexate 10mg tablets | 359 | £1,797 |
| Methofill 20mg/0.4ml inj pre-filled injector | 299 | £18,893 |
| Methofill 15mg/0.3ml inj pre-filled syringes | 279 | £15,785 |
| Methofill 25mg/0.5ml inj pre-filled syringes | 212 | £12,916 |
| Methofill 25mg/0.5ml inj pre-filled injector | 168 | £11,316 |
Compare Methotrexate with
Other medicines in the same BNF section, by prescribing volume.