Medicines
Musculoskeletal and Joint Diseases
Drugs used in rheumatic diseases and gout
Methotrexate

Methotrexate

Name: Methotrexate NHS prescribing in England
Creator: PharmaInsight
License: https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/

Musculoskeletal and Joint Diseases Drugs used in rheumatic diseases and gout BNF 1001030U0

Data updated May 2026 Download CSV

Methotrexate was ranked 122nd of 1,796 medicines by items in May 2026, with 182,888 items, down 3.2% on a year earlier.

182,888items -3.2%

Dispensed in May 2026

1,858,732items

Rolling 12 months

£2,247,752

Net ingredient cost · May 2026

Figure 1. Methotrexate: national items dispensed by month

Source: NHSBSA Prescription Cost Analysis, to May 2026

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Chart: <a href="https://pharmainsight.co.uk/medicines/methotrexate-1001030u0">PharmaInsight</a> · Data: NHSBSA English Prescribing Dataset

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At a glance

Therapeutic class Drugs used in rheumatic diseases and gout
Presentations 15 shown
Average cost / item £12.29
Year on year Down 3.2% on a year earlier

What this is

Net ingredient cost is the list price before discounts and dispensing fees, not what the NHS finally pays.

Top presentations, May 2026

The individual products dispensed under Methotrexate this month.

Presentations of Methotrexate, May 2026
Presentation	BNF code	Items	Net ingredient cost
Methotrexate 2.5mg tablets	1001030U0AAABAB	151,805	£230,463
Metoject PEN 20mg/0.4ml inj pre-filled pens	1001030U0BEARBW	8,966	£601,596
Metoject PEN 15mg/0.3ml inj pre-filled pens	1001030U0BEAXCC	6,160	£392,990
Metoject PEN 25mg/0.5ml inj pre-filled pens	1001030U0BEAWCB	5,966	£412,525
Metoject PEN 10mg/0.2ml inj pre-filled pens	1001030U0BEAZCE	2,624	£152,556
Metoject PEN 17.5mg/0.35ml inj pre-filled pens	1001030U0BEAQBV	1,693	£116,815
Metoject PEN 12.5mg/0.25ml inj pre-filled pens	1001030U0BEAYCD	1,339	£88,769
Metoject PEN 22.5mg/0.45ml inj pre-filled pens	1001030U0BEASBX	926	£65,632
Metoject PEN 7.5mg/0.15ml inj pre-filled pens	1001030U0BEATBY	840	£47,825
Methofill 20mg/0.4ml inj pre-filled syringes	1001030U0BGAPBH	374	£21,314
Methotrexate 10mg tablets	1001030U0AAACAC	362	£1,839
Methofill 15mg/0.3ml inj pre-filled syringes	1001030U0BGAMBG	296	£16,083
Methofill 20mg/0.4ml inj pre-filled injector	1001030U0BGAFBW	289	£18,287
Methofill 25mg/0.5ml inj pre-filled syringes	1001030U0BGARBI	206	£12,987
Methofill 15mg/0.3ml inj pre-filled injector	1001030U0BGADCC	179	£10,570

Source: NHSBSA Prescription Cost Analysis · to May 2026 OGL v3.0

Where Methotrexate is dispensed

The regions and dispensing practices with the highest Methotrexate volumes.

Top regions

Top dispensing practices

Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.

Compare Methotrexate with

Other medicines in the same BNF section, by prescribing volume.

Methotrexate vs Allopurinol Methotrexate vs Naproxen Methotrexate vs Hydroxychloroquine sulfate Methotrexate vs Methylprednisolone acetate Methotrexate vs Ibuprofen

Download this data

The monthly series for Methotrexate is in this page's CSV. For the ranked national series across every medicine, with the method and caveats documented, see the most-prescribed medicines dataset in our open data catalogue.