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PharmaInsight

Methotrexate vs Allopurinol

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Allopurinol was dispensed 3.4× as often as Methotrexate in March 2026 — 640,753 items versus 190,005 in England.

190,005items

Methotrexate · March 2026

NHSBSA Prescription Cost Analysis

640,753items

Allopurinol · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Methotrexate versus Allopurinol: national items dispensed by month

▬ Methotrexate   ·   ╌ Allopurinol

Allopurinol 190,005

Source: NHSBSA Prescription Cost Analysis, to March 2026

Methotrexate versus Allopurinol, March 2026
Measure Methotrexate Allopurinol
Items, March 2026 190,005 640,753
Items, last 12 months 2,236,642 7,494,398
Net ingredient cost, March 2026 £2,295,534 £632,591

See the full profile for Methotrexate or Allopurinol.