Skip to content
PharmaInsight

Amitriptyline hydrochloride vs Agomelatine

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Amitriptyline hydrochloride was dispensed 516.6× as often as Agomelatine in March 2026 — 1,420,123 items versus 2,749 in England.

1,420,123items

Amitriptyline hydrochloride · March 2026

NHSBSA Prescription Cost Analysis

2,749items

Agomelatine · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Amitriptyline hydrochloride versus Agomelatine: national items dispensed by month

▬ Amitriptyline hydrochloride   ·   ╌ Agomelatine

Agomelatine 1,420,123

Source: NHSBSA Prescription Cost Analysis, to March 2026

Amitriptyline hydrochloride versus Agomelatine, March 2026
Measure Amitriptyline hydrochloride Agomelatine
Items, March 2026 1,420,123 2,749
Items, last 12 months 16,560,644 31,387
Net ingredient cost, March 2026 £1,545,559 £84,983

See the full profile for Amitriptyline hydrochloride or Agomelatine.