Amitriptyline hydrochloride vs Clomipramine hydrochloride

National NHS prescribing compared (Prescription Cost Analysis)

Data updated March 2026

Amitriptyline hydrochloride was dispensed 74.6× as often as Clomipramine hydrochloride in March 2026 — 1,420,123 items versus 19,030 in England.

1,420,123items

Amitriptyline hydrochloride · March 2026

NHSBSA Prescription Cost Analysis

19,030items

Clomipramine hydrochloride · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Amitriptyline hydrochloride versus Clomipramine hydrochloride: national items dispensed by month

▬ Amitriptyline hydrochloride · ╌ Clomipramine hydrochloride

Source: NHSBSA Prescription Cost Analysis, to March 2026

Amitriptyline hydrochloride versus Clomipramine hydrochloride, March 2026
Measure	Amitriptyline hydrochloride	Clomipramine hydrochloride
Items, March 2026	1,420,123	19,030
Items, last 12 months	16,560,644	226,844
Net ingredient cost, March 2026	£1,545,559	£218,796