Amitriptyline hydrochloride vs Imipramine hydrochloride

National NHS prescribing compared (Prescription Cost Analysis)

Data updated March 2026

Amitriptyline hydrochloride was dispensed 184.4× as often as Imipramine hydrochloride in March 2026 — 1,420,123 items versus 7,703 in England.

1,420,123items

Amitriptyline hydrochloride · March 2026

NHSBSA Prescription Cost Analysis

7,703items

Imipramine hydrochloride · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Amitriptyline hydrochloride versus Imipramine hydrochloride: national items dispensed by month

▬ Amitriptyline hydrochloride · ╌ Imipramine hydrochloride

Source: NHSBSA Prescription Cost Analysis, to March 2026

Amitriptyline hydrochloride versus Imipramine hydrochloride, March 2026
Measure	Amitriptyline hydrochloride	Imipramine hydrochloride
Items, March 2026	1,420,123	7,703
Items, last 12 months	16,560,644	95,336
Net ingredient cost, March 2026	£1,545,559	£73,931