Amitriptyline hydrochloride vs Venlafaxine
National NHS prescribing compared (Prescription Cost Analysis)
Amitriptyline hydrochloride was dispensed 2.6× as often as Venlafaxine in March 2026 — 1,420,123 items versus 554,493 in England.
1,420,123items
Amitriptyline hydrochloride · March 2026
NHSBSA Prescription Cost Analysis
554,493items
Venlafaxine · March 2026
NHSBSA Prescription Cost Analysis
Figure 1. Amitriptyline hydrochloride versus Venlafaxine: national items dispensed by month
▬ Amitriptyline hydrochloride · ╌ Venlafaxine
Source: NHSBSA Prescription Cost Analysis, to March 2026
| Measure | Amitriptyline hydrochloride | Venlafaxine |
|---|---|---|
| Items, March 2026 | 1,420,123 | 554,493 |
| Items, last 12 months | 16,560,644 | 6,430,122 |
| Net ingredient cost, March 2026 | £1,545,559 | £5,383,757 |
See the full profile for Amitriptyline hydrochloride or Venlafaxine.