Amitriptyline hydrochloride vs Venlafaxine
National NHS prescribing compared (Prescription Cost Analysis)
Amitriptyline hydrochloride was dispensed 2.5× as often as Venlafaxine in May 2026 — 1,353,284 items versus 532,507 in England.
1,353,284items
Amitriptyline hydrochloride · May 2026
NHSBSA Prescription Cost Analysis
532,507items
Venlafaxine · May 2026
NHSBSA Prescription Cost Analysis
Figure 1. Amitriptyline hydrochloride versus Venlafaxine: national items dispensed by month
▬ Amitriptyline hydrochloride · ╌ Venlafaxine
Source: NHSBSA Prescription Cost Analysis, to May 2026
| Measure | Amitriptyline hydrochloride | Venlafaxine |
|---|---|---|
| Items, May 2026 | 1,353,284 | 532,507 |
| Items, last 12 months | 16,564,286 | 6,461,429 |
| Net ingredient cost, May 2026 | £1,443,147 | £5,192,832 |
See the full profile for Amitriptyline hydrochloride or Venlafaxine.