Amitriptyline hydrochloride vs Vortioxetine
National NHS prescribing compared (Prescription Cost Analysis)
Amitriptyline hydrochloride was dispensed 34.0× as often as Vortioxetine in March 2026 — 1,420,123 items versus 41,782 in England.
1,420,123items
Amitriptyline hydrochloride · March 2026
NHSBSA Prescription Cost Analysis
41,782items
Vortioxetine · March 2026
NHSBSA Prescription Cost Analysis
Figure 1. Amitriptyline hydrochloride versus Vortioxetine: national items dispensed by month
▬ Amitriptyline hydrochloride · ╌ Vortioxetine
Source: NHSBSA Prescription Cost Analysis, to March 2026
| Measure | Amitriptyline hydrochloride | Vortioxetine |
|---|---|---|
| Items, March 2026 | 1,420,123 | 41,782 |
| Items, last 12 months | 16,560,644 | 461,407 |
| Net ingredient cost, March 2026 | £1,545,559 | £1,018,343 |
See the full profile for Amitriptyline hydrochloride or Vortioxetine.