Diphenhydramine hydrochloride vs Promethazine hydrochloride
National NHS prescribing compared (Prescription Cost Analysis)
Promethazine hydrochloride was dispensed 104.8× as often as Diphenhydramine hydrochloride in April 2026 — 246,200 items versus 2,350 in England.
2,350items
Diphenhydramine hydrochloride · April 2026
NHSBSA Prescription Cost Analysis
246,200items
Promethazine hydrochloride · April 2026
NHSBSA Prescription Cost Analysis
Figure 1. Diphenhydramine hydrochloride versus Promethazine hydrochloride: national items dispensed by month
▬ Diphenhydramine hydrochloride · ╌ Promethazine hydrochloride
Source: NHSBSA Prescription Cost Analysis, to April 2026
| Measure | Diphenhydramine hydrochloride | Promethazine hydrochloride |
|---|---|---|
| Items, April 2026 | 2,350 | 246,200 |
| Items, last 12 months | 28,933 | 2,913,211 |
| Net ingredient cost, April 2026 | £11,561 | £472,333 |
See the full profile for Diphenhydramine hydrochloride or Promethazine hydrochloride.