Diphenhydramine hydrochloride
Diphenhydramine hydrochloride was ranked 736th of 1,792 medicines by items in May 2026, with 2,222 items, down 9.0% on a year earlier.
Dispensed in May 2026
Rolling 12 months
Net ingredient cost · May 2026
Figure 1. Diphenhydramine hydrochloride: national items dispensed by month
Source: NHSBSA Prescription Cost Analysis, to May 2026
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At a glance
- Therapeutic class Antihistamines, hyposensitisation and allergic emergencies
- Presentations 4 shown
- Average cost / item £5.03
- Year on year Down 9.0% on a year earlier
Top presentations, May 2026
The individual products dispensed under Diphenhydramine hydrochloride this month.
| Presentation | BNF code | Items | Net ingredient cost |
|---|---|---|---|
| Diphenhydramine 50mg tablets | 0304010N0AAAPAP | 1,076 | £5,382 |
| Diphenhydramine 25mg tablets | 0304010N0AAAGAG | 1,046 | £4,934 |
| Nytol One-A-Night 50mg tablets | 0304010N0BFADAP | 94 | £646 |
| Histergan 10mg/5ml syrup | 0304010N0BCABAK | 6 | £208 |
Source: NHSBSA Prescription Cost Analysis · to May 2026 OGL v3.0
Where Diphenhydramine hydrochloride is dispensed
The regions and dispensing practices with the highest Diphenhydramine hydrochloride volumes.
Top regions
Top dispensing practices
Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.
Compare Diphenhydramine hydrochloride with
Other medicines in the same BNF section, by prescribing volume.