Loratadine vs Diphenhydramine hydrochloride
National NHS prescribing compared (Prescription Cost Analysis)
Loratadine was dispensed 50.1× as often as Diphenhydramine hydrochloride in March 2026 — 119,479 items versus 2,386 in England.
119,479items
Loratadine · March 2026
NHSBSA Prescription Cost Analysis
2,386items
Diphenhydramine hydrochloride · March 2026
NHSBSA Prescription Cost Analysis
Figure 1. Loratadine versus Diphenhydramine hydrochloride: national items dispensed by month
▬ Loratadine · ╌ Diphenhydramine hydrochloride
Source: NHSBSA Prescription Cost Analysis, to March 2026
| Measure | Loratadine | Diphenhydramine hydrochloride |
|---|---|---|
| Items, March 2026 | 119,479 | 2,386 |
| Items, last 12 months | 1,441,787 | 28,945 |
| Net ingredient cost, March 2026 | £129,606 | £12,041 |
See the full profile for Loratadine or Diphenhydramine hydrochloride.