Loratadine vs Diphenhydramine hydrochloride
National NHS prescribing compared (Prescription Cost Analysis)
Loratadine was dispensed 52.5× as often as Diphenhydramine hydrochloride in April 2026 — 123,374 items versus 2,350 in England.
123,374items
Loratadine · April 2026
NHSBSA Prescription Cost Analysis
2,350items
Diphenhydramine hydrochloride · April 2026
NHSBSA Prescription Cost Analysis
Figure 1. Loratadine versus Diphenhydramine hydrochloride: national items dispensed by month
▬ Loratadine · ╌ Diphenhydramine hydrochloride
Source: NHSBSA Prescription Cost Analysis, to April 2026
| Measure | Loratadine | Diphenhydramine hydrochloride |
|---|---|---|
| Items, April 2026 | 123,374 | 2,350 |
| Items, last 12 months | 1,434,684 | 28,933 |
| Net ingredient cost, April 2026 | £142,328 | £11,561 |
See the full profile for Loratadine or Diphenhydramine hydrochloride.