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PharmaInsight

Fluoxetine hydrochloride vs Vortioxetine

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Fluoxetine hydrochloride was dispensed 15.6× as often as Vortioxetine in March 2026 — 650,914 items versus 41,782 in England.

650,914items

Fluoxetine hydrochloride · March 2026

NHSBSA Prescription Cost Analysis

41,782items

Vortioxetine · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Fluoxetine hydrochloride versus Vortioxetine: national items dispensed by month

▬ Fluoxetine hydrochloride   ·   ╌ Vortioxetine

Vortioxetine 650,914

Source: NHSBSA Prescription Cost Analysis, to March 2026

Fluoxetine hydrochloride versus Vortioxetine, March 2026
Measure Fluoxetine hydrochloride Vortioxetine
Items, March 2026 650,914 41,782
Items, last 12 months 7,603,442 461,407
Net ingredient cost, March 2026 £2,113,519 £1,018,343

See the full profile for Fluoxetine hydrochloride or Vortioxetine.