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Independent analysis of NHS open data
PharmaInsight

Fluoxetine hydrochloride

Central Nervous System Antidepressant drugs BNF 0403030E0
Data updated May 2026 Download CSV

Fluoxetine hydrochloride was ranked 38th of 1,792 medicines by items in May 2026, with 622,211 items, down 3.4% on a year earlier.

622,211items -3.4%

Dispensed in May 2026

7,600,833items

Rolling 12 months

£1,102,342

Net ingredient cost · May 2026

Figure 1. Fluoxetine hydrochloride: national items dispensed by month

0 332k 664k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 May 2026 622,211 Jan 2021: 597k Feb 2021: 561k Mar 2021: 630k Apr 2021: 609k May 2021: 582k Jun 2021: 618k Jul 2021: 616k Aug 2021: 585k Sep 2021: 616k Oct 2021: 589k Nov 2021: 613k Dec 2021: 638k Jan 2022: 606k Feb 2022: 565k Mar 2022: 638k Apr 2022: 595k May 2022: 621k Jun 2022: 605k Jul 2022: 600k Aug 2022: 614k Sep 2022: 612k Oct 2022: 604k Nov 2022: 616k Dec 2022: 613k Jan 2023: 618k Feb 2023: 571k Mar 2023: 652k Apr 2023: 583k May 2023: 621k Jun 2023: 631k Jul 2023: 614k Aug 2023: 624k Sep 2023: 613k Oct 2023: 622k Nov 2023: 626k Dec 2023: 620k Jan 2024: 641k Feb 2024: 602k Mar 2024: 611k Apr 2024: 630k May 2024: 644k Jun 2024: 601k Jul 2024: 653k Aug 2024: 626k Sep 2024: 615k Oct 2024: 651k Nov 2024: 623k Dec 2024: 638k Jan 2025: 657k Feb 2025: 585k Mar 2025: 619k Apr 2025: 617k May 2025: 644k Jun 2025: 624k Jul 2025: 663k Aug 2025: 606k Sep 2025: 638k Oct 2025: 657k Nov 2025: 605k Dec 2025: 664k Jan 2026: 643k Feb 2026: 591k Mar 2026: 651k Apr 2026: 637k May 2026: 622k

Source: NHSBSA Prescription Cost Analysis, to May 2026

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At a glance

  • Therapeutic class Antidepressant drugs
  • Presentations 11 shown
  • Average cost / item £1.77
  • Year on year Down 3.4% on a year earlier
What this is
Net ingredient cost is the list price before discounts and dispensing fees, not what the NHS finally pays.

Top presentations, May 2026

The individual products dispensed under Fluoxetine hydrochloride this month.

Presentations of Fluoxetine hydrochloride, May 2026
Presentation BNF code Items Net ingredient cost
Fluoxetine 20mg capsules 0403030E0AAAAAA 494,517 £669,211
Fluoxetine 40mg capsules 0403030E0AAANAN 35,165 £57,213
Fluoxetine 60mg capsules 0403030E0AAAEAE 30,181 £34,560
Fluoxetine 10mg capsules 0403030E0AAALAL 28,666 £81,994
Fluoxetine 30mg capsules 0403030E0AAAMAM 20,456 £29,839
Fluoxetine 20mg/5ml oral solution 0403030E0AAACAC 7,844 £113,772
Olena 20mg dispersible tablets 0403030E0BHAAAK 2,621 £12,653
Fluoxetine 20mg/5ml oral solution sugar free 0403030E0AAAHAH 1,616 £23,655
Fluoxetine 10mg tablets 0403030E0AAAPAP 974 £73,578
Prozep 20mg/5ml oral solution 0403030E0BGAAAH 165 £5,815
Prozac 20mg capsules 0403030E0BBAAAA 6 £53

Source: NHSBSA Prescription Cost Analysis · to May 2026 OGL v3.0

Where Fluoxetine hydrochloride is dispensed

The regions and dispensing practices with the highest Fluoxetine hydrochloride volumes.

Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.

Compare Fluoxetine hydrochloride with

Other medicines in the same BNF section, by prescribing volume.