Amitriptyline hydrochloride vs Fluoxetine hydrochloride

National NHS prescribing compared (Prescription Cost Analysis)

Data updated March 2026

Amitriptyline hydrochloride was dispensed 2.2× as often as Fluoxetine hydrochloride in March 2026 — 1,420,123 items versus 650,914 in England.

1,420,123items

Amitriptyline hydrochloride · March 2026

NHSBSA Prescription Cost Analysis

650,914items

Fluoxetine hydrochloride · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Amitriptyline hydrochloride versus Fluoxetine hydrochloride: national items dispensed by month

▬ Amitriptyline hydrochloride · ╌ Fluoxetine hydrochloride

Source: NHSBSA Prescription Cost Analysis, to March 2026

Amitriptyline hydrochloride versus Fluoxetine hydrochloride, March 2026
Measure	Amitriptyline hydrochloride	Fluoxetine hydrochloride
Items, March 2026	1,420,123	650,914
Items, last 12 months	16,560,644	7,603,442
Net ingredient cost, March 2026	£1,545,559	£2,113,519