Leflunomide vs Methotrexate
National NHS prescribing compared (Prescription Cost Analysis)
Methotrexate was dispensed 11.5× as often as Leflunomide in March 2026 — 190,005 items versus 16,479 in England.
16,479items
Leflunomide · March 2026
NHSBSA Prescription Cost Analysis
190,005items
Methotrexate · March 2026
NHSBSA Prescription Cost Analysis
Figure 1. Leflunomide versus Methotrexate: national items dispensed by month
▬ Leflunomide · ╌ Methotrexate
Source: NHSBSA Prescription Cost Analysis, to March 2026
| Measure | Leflunomide | Methotrexate |
|---|---|---|
| Items, March 2026 | 16,479 | 190,005 |
| Items, last 12 months | 197,527 | 2,236,642 |
| Net ingredient cost, March 2026 | £175,680 | £2,295,534 |
See the full profile for Leflunomide or Methotrexate.